Cerebral protection during aneurysm surgery with isoflurane anesthesia. Technical note

F. B. Meyer, D. A. Muzzi

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

A strategy for intraoperative cerebral protection is described in which intraoperative electroencephalography is used to titrate the level of inspired isoflurane given for anesthesia to obtain isoelectricity prior to temporary vessel occlusion during repair of difficult aneurysms. During temporary vessel occlusion, arterial blood pressure is maintained or increased with an inotropic or vasopressor agent. After clipping of the aneurysm, the concentration of isoflurane is reduced to allow the patient to awaken in the operating room for early postoperative neurological examination. The combination of a high concentration of isoflurane, temporary vessel occlusion, and maintenance of arterial blood pressure may be a useful protective regimen during neurovascular procedures.

Original languageEnglish (US)
Pages (from-to)541-543
Number of pages3
JournalJournal of Neurosurgery
Volume76
Issue number3
StatePublished - 1992

Fingerprint

Isoflurane
Aneurysm
Anesthesia
Arterial Pressure
Neurologic Examination
Vasoconstrictor Agents
Operating Rooms
Electroencephalography
Maintenance

Keywords

  • aneurysm
  • cerebral protection
  • electroencephalography
  • isoflurane

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Cerebral protection during aneurysm surgery with isoflurane anesthesia. Technical note. / Meyer, F. B.; Muzzi, D. A.

In: Journal of Neurosurgery, Vol. 76, No. 3, 1992, p. 541-543.

Research output: Contribution to journalArticle

Meyer, F. B. ; Muzzi, D. A. / Cerebral protection during aneurysm surgery with isoflurane anesthesia. Technical note. In: Journal of Neurosurgery. 1992 ; Vol. 76, No. 3. pp. 541-543.
@article{205ba81541b049d7954a7bf0f4a2a414,
title = "Cerebral protection during aneurysm surgery with isoflurane anesthesia. Technical note",
abstract = "A strategy for intraoperative cerebral protection is described in which intraoperative electroencephalography is used to titrate the level of inspired isoflurane given for anesthesia to obtain isoelectricity prior to temporary vessel occlusion during repair of difficult aneurysms. During temporary vessel occlusion, arterial blood pressure is maintained or increased with an inotropic or vasopressor agent. After clipping of the aneurysm, the concentration of isoflurane is reduced to allow the patient to awaken in the operating room for early postoperative neurological examination. The combination of a high concentration of isoflurane, temporary vessel occlusion, and maintenance of arterial blood pressure may be a useful protective regimen during neurovascular procedures.",
keywords = "aneurysm, cerebral protection, electroencephalography, isoflurane",
author = "Meyer, {F. B.} and Muzzi, {D. A.}",
year = "1992",
language = "English (US)",
volume = "76",
pages = "541--543",
journal = "Journal of Neurosurgery",
issn = "0022-3085",
publisher = "American Association of Neurological Surgeons",
number = "3",

}

TY - JOUR

T1 - Cerebral protection during aneurysm surgery with isoflurane anesthesia. Technical note

AU - Meyer, F. B.

AU - Muzzi, D. A.

PY - 1992

Y1 - 1992

N2 - A strategy for intraoperative cerebral protection is described in which intraoperative electroencephalography is used to titrate the level of inspired isoflurane given for anesthesia to obtain isoelectricity prior to temporary vessel occlusion during repair of difficult aneurysms. During temporary vessel occlusion, arterial blood pressure is maintained or increased with an inotropic or vasopressor agent. After clipping of the aneurysm, the concentration of isoflurane is reduced to allow the patient to awaken in the operating room for early postoperative neurological examination. The combination of a high concentration of isoflurane, temporary vessel occlusion, and maintenance of arterial blood pressure may be a useful protective regimen during neurovascular procedures.

AB - A strategy for intraoperative cerebral protection is described in which intraoperative electroencephalography is used to titrate the level of inspired isoflurane given for anesthesia to obtain isoelectricity prior to temporary vessel occlusion during repair of difficult aneurysms. During temporary vessel occlusion, arterial blood pressure is maintained or increased with an inotropic or vasopressor agent. After clipping of the aneurysm, the concentration of isoflurane is reduced to allow the patient to awaken in the operating room for early postoperative neurological examination. The combination of a high concentration of isoflurane, temporary vessel occlusion, and maintenance of arterial blood pressure may be a useful protective regimen during neurovascular procedures.

KW - aneurysm

KW - cerebral protection

KW - electroencephalography

KW - isoflurane

UR - http://www.scopus.com/inward/record.url?scp=0026555622&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026555622&partnerID=8YFLogxK

M3 - Article

C2 - 1738037

AN - SCOPUS:0026555622

VL - 76

SP - 541

EP - 543

JO - Journal of Neurosurgery

JF - Journal of Neurosurgery

SN - 0022-3085

IS - 3

ER -