TY - JOUR
T1 - Cerebellar infarction in a patient with cerebral vein thrombosis and patent foramen ovale
T2 - Brain-to-brain embolism?
AU - La Spina, P.
AU - Calabrò, R. S.
AU - Casella, C.
AU - Savica, R.
AU - Granata, F.
AU - Musolino, R.
PY - 2012/3/23
Y1 - 2012/3/23
N2 - Although the association between PFO and cryptogenic stroke is well shown in young adults, the causality is still unclear. The pathogenetic mechanism of ischemic stroke related to PFO is not entirely understood. Indeed, besides the well-known paradoxical embolism, formations of thrombi in situ, especially in the presence of ASA, a higher incidence of atrial fibrillation have been often observed. Cerebral sinus venous thrombosis may be due to local inflammation or to acquired or genetic thrombophilia including hyperhomocysteinemia. We report a case of a young man presenting with a cerebellar infarction probably secondary to a paradoxical brain-to-brain embolism, in which the only detectable embolic source was a cerebral vein thrombosis.
AB - Although the association between PFO and cryptogenic stroke is well shown in young adults, the causality is still unclear. The pathogenetic mechanism of ischemic stroke related to PFO is not entirely understood. Indeed, besides the well-known paradoxical embolism, formations of thrombi in situ, especially in the presence of ASA, a higher incidence of atrial fibrillation have been often observed. Cerebral sinus venous thrombosis may be due to local inflammation or to acquired or genetic thrombophilia including hyperhomocysteinemia. We report a case of a young man presenting with a cerebellar infarction probably secondary to a paradoxical brain-to-brain embolism, in which the only detectable embolic source was a cerebral vein thrombosis.
KW - Cardioembolism
KW - Cerebellar infarction
KW - Cerebral vein thrombosis
UR - http://www.scopus.com/inward/record.url?scp=84883522959&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84883522959&partnerID=8YFLogxK
U2 - 10.1007/s10072-011-0908-6
DO - 10.1007/s10072-011-0908-6
M3 - Article
C2 - 22210158
AN - SCOPUS:84883522959
SN - 1590-1874
VL - 33
SP - 1415
EP - 1417
JO - Neurological Sciences
JF - Neurological Sciences
IS - 6
ER -