Abstract
A selective subtotal cerebellar neuronal degeneration was found in a patient who died 4 1/2 months after suffering neuroleptic malignant syndrome (NMS), a rare, potentially fatal disorder associated with neuroleptic medications. It is suggested that the cerebellar neuronal degeneration in this case was due to hyperpyrexia, a cardial clinical feature of NMS. Similar pathologic findings appear not to have been previously reported in NMS but have been described in heat-induced central nervous system (CNS) injury. The findings imply that a cerebellar syndrome might be encountered in patients who survive NMS complicated by a particularly high febrile course.
Original language | English (US) |
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Pages (from-to) | 387-391 |
Number of pages | 5 |
Journal | Journal of Neurology Neurosurgery and Psychiatry |
Volume | 52 |
Issue number | 3 |
DOIs | |
State | Published - 1989 |
ASJC Scopus subject areas
- Surgery
- Clinical Neurology
- Psychiatry and Mental health