Centrosomes: Sfi1p and Centrin Unravel a Structural Riddle

Jeffrey L. Salisbury

doi:10.1016/j.cub.2003.12.019

Centrosomes: Sfi1p and Centrin Unravel a Structural Riddle

Jeffrey L. Salisbury

Biochemistry and Molecular Biology

Research output: Contribution to journal › Review article › peer-review

56 Scopus citations

Abstract

The discovery of Sfi1p as a novel binding partner for the Ca ²⁺-binding protein centrin has provided new insight into the dynamic behavior of centrosomes. Sfi1 binds to multiple centrin molecules along a series of internal repeats, and the complex forms Ca²⁺-sensitive contractile fibers that function to reorient centrioles and alter centrosome structure.

Original language	English (US)
Pages (from-to)	R27-R29
Journal	Current Biology
Volume	14
Issue number	1
DOIs	https://doi.org/10.1016/j.cub.2003.12.019
State	Published - Jan 6 2004

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology
General Agricultural and Biological Sciences

Access to Document

10.1016/j.cub.2003.12.019

Cite this

@article{1b063fdb0900401d8937350300c6e478,

title = "Centrosomes: Sfi1p and Centrin Unravel a Structural Riddle",

abstract = "The discovery of Sfi1p as a novel binding partner for the Ca 2+-binding protein centrin has provided new insight into the dynamic behavior of centrosomes. Sfi1 binds to multiple centrin molecules along a series of internal repeats, and the complex forms Ca2+-sensitive contractile fibers that function to reorient centrioles and alter centrosome structure.",

author = "Salisbury, {Jeffrey L.}",

year = "2004",

month = jan,

day = "6",

doi = "10.1016/j.cub.2003.12.019",

language = "English (US)",

volume = "14",

pages = "R27--R29",

journal = "Current Biology",

issn = "0960-9822",

publisher = "Cell Press",

number = "1",

}

TY - JOUR

T1 - Centrosomes

T2 - Sfi1p and Centrin Unravel a Structural Riddle

AU - Salisbury, Jeffrey L.

PY - 2004/1/6

Y1 - 2004/1/6

N2 - The discovery of Sfi1p as a novel binding partner for the Ca 2+-binding protein centrin has provided new insight into the dynamic behavior of centrosomes. Sfi1 binds to multiple centrin molecules along a series of internal repeats, and the complex forms Ca2+-sensitive contractile fibers that function to reorient centrioles and alter centrosome structure.

AB - The discovery of Sfi1p as a novel binding partner for the Ca 2+-binding protein centrin has provided new insight into the dynamic behavior of centrosomes. Sfi1 binds to multiple centrin molecules along a series of internal repeats, and the complex forms Ca2+-sensitive contractile fibers that function to reorient centrioles and alter centrosome structure.

UR - http://www.scopus.com/inward/record.url?scp=0348226550&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0348226550&partnerID=8YFLogxK

U2 - 10.1016/j.cub.2003.12.019

DO - 10.1016/j.cub.2003.12.019

M3 - Review article

C2 - 14711432

AN - SCOPUS:0348226550

SN - 0960-9822

VL - 14

SP - R27-R29

JO - Current Biology

JF - Current Biology

IS - 1

ER -

Centrosomes: Sfi1p and Centrin Unravel a Structural Riddle

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this