Abstract
The centrosome consists of a pair of centrioles and a surrounding matrix of pericentriolar material that anchors microtubule nucleation sites and consequently determines the number and organization of microtubules in interphase and mitotic cells. Recent studies utilizing a functional genomics approach in the nematode worm Caenorhabditis elegans and sophisticated light and electron microscopy techniques provide new insight into how centrioles act as centrosomal organizers and use a centriolar structural element to dictate centrosome size by defining their capacity to recruit pericentriolar material.
Original language | English (US) |
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Pages (from-to) | 340-343 |
Number of pages | 4 |
Journal | Trends in Cell Biology |
Volume | 13 |
Issue number | 7 |
DOIs | |
State | Published - Jul 1 2003 |
ASJC Scopus subject areas
- Cell Biology