Central venous pressure and ultrasonographic measurement correlation and their associations with intradialytic adverse events in hospitalized patients

A prospective observational study

Hiroshi Sekiguchi, Luke A. Seaburg, Jun Suzuki, Walter J. Astorne, Anil S. Patel, A. Scott Keller, Ognjen Gajic, Kianoush B. Kashani

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Purpose: To investigate correlation of central venous pressure (CVP) with ultrasonographic measurement of central veins, along with association between these variables and occurrence of intradialytic adverse events in hospitalized patients. Materials and methods: Patients requiring hemodialysis via dialysis catheter were prospectively enrolled. CVP measurements through catheter, internal jugular vein aspect ratio, subclavian vein collapsibility, inferior vena cava (IVC) maximal diameter, and IVC collapsibility were recorded before and after hemodialysis. Predictive accuracy of ultrasonographic measurements in discriminating high versus low CVP and their association with intradialytic adverse events were evaluated. Area under receiver operating characteristic curves (AUCs) were calculated. Results: Fifty-nine patients were enrolled. Median (interquartile range) pre- and post-dialysis CVPs were 8 (4–13) mm Hg and 6 (3–10) mm Hg, respectively (P < 0.01). In pre-dialysis, IVC collapsibility had the highest AUC (0.79, P < 0.01) to predict CVP > 8 mm Hg. In post-dialysis, IVC maximal diameter had the highest AUC (0.86, P < 0.01) to predict CVP ≤ 4 mm Hg. Fifteen patients (25%) had adverse events. Neither pre-dialytic CVP nor ultrasonographic variables were associated with occurrence of adverse events. Conclusions: Highest accuracy in predicting low and high CVP was observed with ultrasonographic assessment of IVC diameter and collapsibility. Adverse events were not predicted by pre-dialytic CVP or ultrasonographic measurements.

Original languageEnglish (US)
Pages (from-to)168-174
Number of pages7
JournalJournal of Critical Care
Volume44
DOIs
StatePublished - Apr 1 2018

Fingerprint

Central Venous Pressure
Observational Studies
Prospective Studies
Inferior Vena Cava
Dialysis
Area Under Curve
Renal Dialysis
Catheters
Subclavian Vein
Jugular Veins
ROC Curve
Veins

Keywords

  • Central venous pressure
  • Dry weight
  • Hemodialysis
  • Intradialytic adverse events
  • Ultrasonography

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

Cite this

Central venous pressure and ultrasonographic measurement correlation and their associations with intradialytic adverse events in hospitalized patients : A prospective observational study. / Sekiguchi, Hiroshi; Seaburg, Luke A.; Suzuki, Jun; Astorne, Walter J.; Patel, Anil S.; Keller, A. Scott; Gajic, Ognjen; Kashani, Kianoush B.

In: Journal of Critical Care, Vol. 44, 01.04.2018, p. 168-174.

Research output: Contribution to journalArticle

Sekiguchi, Hiroshi ; Seaburg, Luke A. ; Suzuki, Jun ; Astorne, Walter J. ; Patel, Anil S. ; Keller, A. Scott ; Gajic, Ognjen ; Kashani, Kianoush B. / Central venous pressure and ultrasonographic measurement correlation and their associations with intradialytic adverse events in hospitalized patients : A prospective observational study. In: Journal of Critical Care. 2018 ; Vol. 44. pp. 168-174.
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abstract = "Purpose: To investigate correlation of central venous pressure (CVP) with ultrasonographic measurement of central veins, along with association between these variables and occurrence of intradialytic adverse events in hospitalized patients. Materials and methods: Patients requiring hemodialysis via dialysis catheter were prospectively enrolled. CVP measurements through catheter, internal jugular vein aspect ratio, subclavian vein collapsibility, inferior vena cava (IVC) maximal diameter, and IVC collapsibility were recorded before and after hemodialysis. Predictive accuracy of ultrasonographic measurements in discriminating high versus low CVP and their association with intradialytic adverse events were evaluated. Area under receiver operating characteristic curves (AUCs) were calculated. Results: Fifty-nine patients were enrolled. Median (interquartile range) pre- and post-dialysis CVPs were 8 (4–13) mm Hg and 6 (3–10) mm Hg, respectively (P < 0.01). In pre-dialysis, IVC collapsibility had the highest AUC (0.79, P < 0.01) to predict CVP > 8 mm Hg. In post-dialysis, IVC maximal diameter had the highest AUC (0.86, P < 0.01) to predict CVP ≤ 4 mm Hg. Fifteen patients (25{\%}) had adverse events. Neither pre-dialytic CVP nor ultrasonographic variables were associated with occurrence of adverse events. Conclusions: Highest accuracy in predicting low and high CVP was observed with ultrasonographic assessment of IVC diameter and collapsibility. Adverse events were not predicted by pre-dialytic CVP or ultrasonographic measurements.",
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AU - Astorne, Walter J.

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