Central sensitization, chronic pain, and other symptoms: Better understanding, better management

Mary M. Volcheck, Stephanie M. Graham, Kevin C. Fleming, Arya B. Mohabbat, Connie A. Luedtke

Research output: Contribution to journalArticlepeer-review

Abstract

Central sensitization, a pathophysiologic process in which the central nervous system undergoes changes that alter its processing of pain and other sensory stimuli, may be the mechanism underlying various conditions in which patients have unexplained pain and fatigue. Patients frequently misunderstand the cause of their symptoms and pursue unnecessary evaluations and treatments. Clinicians have a pivotal role in decreasing this misunderstanding by providing patient education, which can affect perception, management, functional status, and quality of life.

Original languageEnglish (US)
Pages (from-to)245-254
Number of pages10
JournalCleveland Clinic journal of medicine
Volume90
Issue number4
DOIs
StatePublished - 2023

ASJC Scopus subject areas

  • General Medicine

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