Central nervous system imaging findings of hemophagocytic syndrome

Tara L. Anderson, Carrie Carr, Timothy J Kaufmann

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

We present a rare case of intracranial involvement in hemophagocytic lymphohistiocytosis (HLH) in an adult patient. MRI features in HLH may mimic those of other neoplastic, infectious, or inflammatory disorders. Key imaging findings correlate to central nervous system inflammation and include diffuse leptomeningeal enhancement, white matter changes with variable enhancement, hemorrhage, and restricted diffusion. Recognition of the imaging characteristic in correlation with clinical presentation, laboratory values, and biopsy findings is essential for making a correct diagnosis.

Original languageEnglish (US)
Pages (from-to)1090-1094
Number of pages5
JournalClinical Imaging
Volume39
Issue number6
DOIs
StatePublished - Nov 1 2015

Keywords

  • Central nervous system
  • Hemophagocytic lymphohistiocytosis
  • Inflammatory
  • MRI

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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