@article{54f1d5b56ef04da0b791a1cf8cde05a4,
title = "Cellular signaling in PKD: foreword",
abstract = "This monograph is dedicated to the memory of Dr. Jared James Grantham (1936–2016), a wonderful man, a compassionate physician, a passionate researcher, and an exceptional scientist. Without his vision, achievements and impact on countless collaborators and disciples, the field of Polycystic Kidney Disease would not be where it is today. His intellect, tenacity, modesty and kindness continue to be an inspiration to all.",
author = "Torres, {Vicente E.} and Ong, {Albert C.M.}",
note = "Funding Information: Beyond Polycystic Kidney Disease, Dr. Grantham made many other contributions to Nephrology, was the founding Editor of the Journal of the American Society of Nephrology, served as Secretary-Treasurer of the Society, and was the founding Director of the Kidney Institute of the University of Kansas. He has been the recipient of numerous awards and recognitions. From the American Society of Nephrology, he received the Homer Smith Award in 1992 and the John P. Peters Award in 2011. He was the recipient of the Lillian Jean Kaplan International Prize for Advancement in the Understanding of Polycystic Kidney Disease from the International Society of Nephrology and the PKD Foundation; the Jean Hamburger Award from the International Society of Nephrology; the David Hume Award from the National Kidney Foundation; and the Scientific Council's Distinguished Achievement Award and the Award of Merit from the American Heart Association. Dr. Grantham was designated a University of Kansas Distinguished Professor and the Harry Statland Professor of Nephrology. Funding Information: Having savored the joy of medical research and decided that this was how he wanted to spend his life, “From Fish to Philosopher” by Homer W. Smith became his Bible. After a residency in Internal Medicine at the University of Kansas (1962–1964), he was accepted for a two-year research fellowship in the National Heart Institute's Laboratory of Kidney and Electrolyte Metabolism under the mentorship of Robert W. Berliner, Jack Orloff and Maurice B. Burg. During these two years, he perfected the microdissection of renal tubules without enzymatic digestion, developed a pipette to collect urine from microperfused tubules, discovered that the collecting duct was the site for the action of vasopressin to concentrate the urine, and that this effect was mediated by cyclic AMP [ 2 , 3 ]. He stayed as a staff investigator at the National Institutes of Health for three additional years during which he showed with Charles E. Ganote how water flows through the cellular layer of collecting ducts [ 4 , 5 ] and demonstrated with Maurice B. Burg that the collecting duct was the site of the sodium‑potassium exchange process critical to maintain potassium balance [ 6 ]. Publisher Copyright: {\textcopyright} 2020",
year = "2020",
month = jul,
doi = "10.1016/j.cellsig.2020.109625",
language = "English (US)",
volume = "71",
journal = "Cellular Signalling",
issn = "0898-6568",
publisher = "Elsevier Inc.",
}