Cellular composition of the tumor microenvironment

Stephen Maxted Ansell, Robert H. Vonderheide

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

In addition to malignant cells, the tumor microenvironment also includes nonmalignant cells, secreted proteins, and blood vessels that surround and support the growth of the tumor. Interactions between the various components of the tumor microenvironment are significant; tumor cells can change the nature of the microenvironment, and conversely, the microenvironment can affect how a tumor grows and spreads. The structure and composition of the tumor microenvironment varies among different types of cancers and between patients. This paper focuses on the composition and function of the tumor microenvironment in hematologic malignancies with a specific focus on B-cell lymphomas.

Fingerprint

Tumor Microenvironment
Neoplasms
Cellular Microenvironment
B-Cell Lymphoma
Hematologic Neoplasms
Blood Vessels
Growth
Proteins

ASJC Scopus subject areas

  • Medicine(all)

Cite this

@article{dadd9438ebea464da19e7cbe11b828b6,
title = "Cellular composition of the tumor microenvironment",
abstract = "In addition to malignant cells, the tumor microenvironment also includes nonmalignant cells, secreted proteins, and blood vessels that surround and support the growth of the tumor. Interactions between the various components of the tumor microenvironment are significant; tumor cells can change the nature of the microenvironment, and conversely, the microenvironment can affect how a tumor grows and spreads. The structure and composition of the tumor microenvironment varies among different types of cancers and between patients. This paper focuses on the composition and function of the tumor microenvironment in hematologic malignancies with a specific focus on B-cell lymphomas.",
author = "Ansell, {Stephen Maxted} and Vonderheide, {Robert H.}",
year = "2013",
doi = "10.1200/EdBook_AM.2013.33.e91",
language = "English (US)",
journal = "American Society of Clinical Oncology educational book / ASCO. American Society of Clinical Oncology. Meeting",
issn = "1548-8756",
publisher = "American Society of Clinical Oncology",

}

TY - JOUR

T1 - Cellular composition of the tumor microenvironment

AU - Ansell, Stephen Maxted

AU - Vonderheide, Robert H.

PY - 2013

Y1 - 2013

N2 - In addition to malignant cells, the tumor microenvironment also includes nonmalignant cells, secreted proteins, and blood vessels that surround and support the growth of the tumor. Interactions between the various components of the tumor microenvironment are significant; tumor cells can change the nature of the microenvironment, and conversely, the microenvironment can affect how a tumor grows and spreads. The structure and composition of the tumor microenvironment varies among different types of cancers and between patients. This paper focuses on the composition and function of the tumor microenvironment in hematologic malignancies with a specific focus on B-cell lymphomas.

AB - In addition to malignant cells, the tumor microenvironment also includes nonmalignant cells, secreted proteins, and blood vessels that surround and support the growth of the tumor. Interactions between the various components of the tumor microenvironment are significant; tumor cells can change the nature of the microenvironment, and conversely, the microenvironment can affect how a tumor grows and spreads. The structure and composition of the tumor microenvironment varies among different types of cancers and between patients. This paper focuses on the composition and function of the tumor microenvironment in hematologic malignancies with a specific focus on B-cell lymphomas.

UR - http://www.scopus.com/inward/record.url?scp=84952333402&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84952333402&partnerID=8YFLogxK

U2 - 10.1200/EdBook_AM.2013.33.e91

DO - 10.1200/EdBook_AM.2013.33.e91

M3 - Article

C2 - 23714465

AN - SCOPUS:84952333402

JO - American Society of Clinical Oncology educational book / ASCO. American Society of Clinical Oncology. Meeting

JF - American Society of Clinical Oncology educational book / ASCO. American Society of Clinical Oncology. Meeting

SN - 1548-8756

ER -