Cell adhesion molecules in the development of the Drosophila nervous system

A. J. Bieber

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

Differential cell adhesion plays an essential role in the development of the Drosophila nervous system. Proteins that are involved in these adhesive interactions have been identified and characterized. Many of these molecules contain structural motifs that have previously been identified in cell adhesion molecules in vertebrates, suggesting that vertebrates and invertebrates may share many of the same molecular mechanisms of neuronal recognition and adhesion. Mutations in many of these adhesion molecules have now been identified; the classical and molecular genetic techniques that are the strengths of the Drosophila experimental system promise to be powerful tools for studying the role of cell adhesion molecules in the development of the nervous system.

Original languageEnglish (US)
Pages (from-to)309-320
Number of pages12
JournalSeminars in Neuroscience
Volume3
Issue number4
DOIs
StatePublished - Aug 1991

Keywords

  • Drosophila
  • axon pathfinding
  • cell adhesion
  • neuronal development

ASJC Scopus subject areas

  • Neuroscience(all)

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