Celiac disease: a clinical review

Badr Al-Bawardy, D. Chamil Codipilly, Alberto Rubio Tapia, David H. Bruining, Stephanie L. Hansel, Joseph A. Murray

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

Celiac disease (CD) is an immune-mediated inflammatory enteropathy triggered by gluten exposure in genetically susceptible individuals. It has a high prevalence approaching 1% of the US population. A high index of suspicion is warranted to diagnose CD as frequently patients present with extraintestinal or atypical manifestations. CD is diagnosed by a combination of serum serologies and duodenal biopsies. The majority of patients will respond to a lifelong gluten-free diet which is the cornerstone of therapy. Complications such as refractory CD, ulcerative jejunoileitis, enteropathy associated T-cell lymphoma and small bowel adenocarcinoma occur in a minority of patients.

Original languageEnglish (US)
Pages (from-to)1-10
Number of pages10
JournalAbdominal Radiology
DOIs
StateAccepted/In press - Jan 12 2017

Keywords

  • Celiac disease
  • Enteropathy
  • Gluten free
  • imaging
  • Refractory
  • Sprue

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology
  • Urology
  • Radiological and Ultrasound Technology

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  • Cite this

    Al-Bawardy, B., Codipilly, D. C., Rubio Tapia, A., Bruining, D. H., Hansel, S. L., & Murray, J. A. (Accepted/In press). Celiac disease: a clinical review. Abdominal Radiology, 1-10. https://doi.org/10.1007/s00261-016-1034-y