Celiac disease: a clinical review

Badr Al-Bawardy, D. Chamil Codipilly, Alberto Rubio-Tapia, David H. Bruining, Stephanie L. Hansel, Joseph A. Murray

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

Celiac disease (CD) is an immune-mediated inflammatory enteropathy triggered by gluten exposure in genetically susceptible individuals. It has a high prevalence approaching 1% of the US population. A high index of suspicion is warranted to diagnose CD as frequently patients present with extraintestinal or atypical manifestations. CD is diagnosed by a combination of serum serologies and duodenal biopsies. The majority of patients will respond to a lifelong gluten-free diet which is the cornerstone of therapy. Complications such as refractory CD, ulcerative jejunoileitis, enteropathy associated T-cell lymphoma and small bowel adenocarcinoma occur in a minority of patients.

Original languageEnglish (US)
Pages (from-to)351-360
Number of pages10
JournalAbdominal Radiology
Volume42
Issue number2
DOIs
StatePublished - Feb 1 2017

Keywords

  • Celiac disease
  • Enteropathy
  • Gluten free
  • Refractory
  • Sprue
  • imaging

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Gastroenterology
  • Urology

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