Abstract
Celiac disease (CD) is an immune-mediated inflammatory enteropathy triggered by gluten exposure in genetically susceptible individuals. It has a high prevalence approaching 1% of the US population. A high index of suspicion is warranted to diagnose CD as frequently patients present with extraintestinal or atypical manifestations. CD is diagnosed by a combination of serum serologies and duodenal biopsies. The majority of patients will respond to a lifelong gluten-free diet which is the cornerstone of therapy. Complications such as refractory CD, ulcerative jejunoileitis, enteropathy associated T-cell lymphoma and small bowel adenocarcinoma occur in a minority of patients.
Original language | English (US) |
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Pages (from-to) | 351-360 |
Number of pages | 10 |
Journal | Abdominal Radiology |
Volume | 42 |
Issue number | 2 |
DOIs | |
State | Published - Feb 1 2017 |
Keywords
- Celiac disease
- Enteropathy
- Gluten free
- Refractory
- Sprue
- imaging
ASJC Scopus subject areas
- Radiological and Ultrasound Technology
- Radiology Nuclear Medicine and imaging
- Gastroenterology
- Urology