CCL18 in a multiplex urine-based assay for the detection of bladder cancer

Virginia Urquidi; Jeongsoon Kim; Myron Chang; Yunfeng Dai; Charles J. Rosser; Steve Goodison

doi:10.1371/journal.pone.0037797

CCL18 in a multiplex urine-based assay for the detection of bladder cancer

Virginia Urquidi, Jeongsoon Kim, Myron Chang, Yunfeng Dai, Charles J. Rosser, Steve Goodison

Quantitative Health Sciences

Research output: Contribution to journal › Article › peer-review

62 Scopus citations

Abstract

The early detection of bladder cancer (BCa) is pivotal for successful patient treatment and management. Through genomic and proteomic studies, we have identified a number of bladder cancer-associated biomarkers that have potential clinical utility. In a case-control study, we examined voided urines from 127 subjects: 64 tumor-bearing subjects and 63 controls. The urine concentrations of the following proteins were assessed by enzyme-linked immunosorbent assay (ELISA); C-C motif chemokine 18 (CCL18), Plasminogen Activator Inhibitor 1 (PAI-1) and CD44. Data were compared to a commercial ELISA-based BCa detection assay (BTA-Trak

Original language	English (US)
Article number	e37797
Journal	PloS one
Volume	7
Issue number	5
DOIs	https://doi.org/10.1371/journal.pone.0037797
State	Published - May 21 2012

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology
General Agricultural and Biological Sciences
General

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AU - Goodison, Steve

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CCL18 in a multiplex urine-based assay for the detection of bladder cancer

Abstract

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