Cataplexy emotional trigger questionnaire (CETQ) - A brief patient screen to identify cataplexy in patients with narcolepsy

Wendy R. Moore, Micheal H. Silber, Paul A. Decker, Patricia C. Heim-Penokie, Vicki K. Sikkink, Nancy Slocumb, Jarrett W. Richardson, Lois Elaine Krahn

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Study Objectives: This pilot study explored the sensitivity and specificity of a brief survey to determine the presence of cataplexy. We hypothesized that the brief questionnaire could provide a quick, sensitive, and specific screening tool to identify those patients with cataplexy, which would result in more timely referrals for further diagnostic testing. Design: The pilot study utilized a brief questionnaire that was developed by including 5 questions that were found to be strong positive predictors of cataplexy from a previous 51-item cataplexy questionnaire. Setting: Participants with a laboratory-confirmed diagnosis completed the questionnaire via mail correspondence or at the time of scheduled appointments in the Mayo Clinic Sleep Disorder Center, Rochester, Minn. Participants: Seventy-eight patients with narcolepsy and cataplexy and 78 patients with obstructive sleep apnea completed the questionnaire. Interventions: NA. Measurements and Results: The sensitivity, specificity, area under the curve, positive predictive value, and negative predictive value/ were computed for each question individually, along with appropriate 95% confidence intervals. Conclusions: The first item of the cataplexy emotional trigger questionnaire (CETQ) discriminates patients with cataplexy from controls with excellent sensitivity and specificity. The addition of the other 4 questions, in the context of question 1, did not improve specificity, area under the curve, positive predictive value, or negative predictive value but did provide useful confirmatory data. Thus, a single question provides a brief practical tool that could improve the recognition of cataplexy in the clinical setting. Depending on the circumstance, users may be interested in utilizing 1 or all 5 questions.

Original languageEnglish (US)
Pages (from-to)37-40
Number of pages4
JournalJournal of Clinical Sleep Medicine
Volume3
Issue number1
StatePublished - Feb 15 2007

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Cataplexy
Narcolepsy
Sensitivity and Specificity
Area Under Curve
Surveys and Questionnaires
Clinical Laboratory Techniques
Postal Service
Obstructive Sleep Apnea
Appointments and Schedules
Referral and Consultation
Confidence Intervals

Keywords

  • Cataplexy
  • Diagnosis
  • Narcolepsy
  • Screen

ASJC Scopus subject areas

  • Clinical Neurology
  • Pulmonary and Respiratory Medicine
  • Neurology

Cite this

Moore, W. R., Silber, M. H., Decker, P. A., Heim-Penokie, P. C., Sikkink, V. K., Slocumb, N., ... Krahn, L. E. (2007). Cataplexy emotional trigger questionnaire (CETQ) - A brief patient screen to identify cataplexy in patients with narcolepsy. Journal of Clinical Sleep Medicine, 3(1), 37-40.

Cataplexy emotional trigger questionnaire (CETQ) - A brief patient screen to identify cataplexy in patients with narcolepsy. / Moore, Wendy R.; Silber, Micheal H.; Decker, Paul A.; Heim-Penokie, Patricia C.; Sikkink, Vicki K.; Slocumb, Nancy; Richardson, Jarrett W.; Krahn, Lois Elaine.

In: Journal of Clinical Sleep Medicine, Vol. 3, No. 1, 15.02.2007, p. 37-40.

Research output: Contribution to journalArticle

Moore, WR, Silber, MH, Decker, PA, Heim-Penokie, PC, Sikkink, VK, Slocumb, N, Richardson, JW & Krahn, LE 2007, 'Cataplexy emotional trigger questionnaire (CETQ) - A brief patient screen to identify cataplexy in patients with narcolepsy', Journal of Clinical Sleep Medicine, vol. 3, no. 1, pp. 37-40.
Moore WR, Silber MH, Decker PA, Heim-Penokie PC, Sikkink VK, Slocumb N et al. Cataplexy emotional trigger questionnaire (CETQ) - A brief patient screen to identify cataplexy in patients with narcolepsy. Journal of Clinical Sleep Medicine. 2007 Feb 15;3(1):37-40.
Moore, Wendy R. ; Silber, Micheal H. ; Decker, Paul A. ; Heim-Penokie, Patricia C. ; Sikkink, Vicki K. ; Slocumb, Nancy ; Richardson, Jarrett W. ; Krahn, Lois Elaine. / Cataplexy emotional trigger questionnaire (CETQ) - A brief patient screen to identify cataplexy in patients with narcolepsy. In: Journal of Clinical Sleep Medicine. 2007 ; Vol. 3, No. 1. pp. 37-40.
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