Ca2+ uptake and Cd2+ accumulation in larval tilapia (Oreochromis mossambicus) acclimated to waterborne Cd2+

Min Hwang Chang, Hui Chen Lin, Pung Pung Hwang

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

The present study compares the rates of Ca2+ uptake and Cd2+ accumulation in tilapia (Oreochromis mossambicus) between larvae preexposed to Cd2+ and naive larvae. Preexposure to Cd2+ induces some form of adaptation that attenuates the effects of Cd2+ later on. Exposure to Cd2+ decreased the uptake of Ca2+ but did not suppress the accumulation rate of Cd2+. A 12-fold increase in 96-h half-maximal lethal concentration was found in tilapia larvae preexposed to 0.45 μM Cd2+ from hatching for 3 days in comparison with naive 3-day-old larvae. The effects of Cd2+ on Ca2+ influx kinetics in larvae preexposed to 0.18 μM Cd2+ for 3 days were examined. The Michaelis constant for Ca2+ in the 0.18 μM Cd2+ preexposed larvae did not change significantly in the presence of Cd2+, whereas maximal velocity increased by ~23%. An enhanced Ca2+ uptake efficiency (~18%) was found in these Cd2+-acclimated larvae. The criterion that determines the survival of tilapia larvae encountering Cd2+ challenge is the degree of interference with Ca2+ homeostasis instead of the absolute amount of Cd2+ accumulated.

Original languageEnglish (US)
Pages (from-to)R1570-R1577
JournalAmerican Journal of Physiology - Regulatory Integrative and Comparative Physiology
Volume274
Issue number6 43-6
DOIs
StatePublished - Jan 1 1998

Keywords

  • Acclimation
  • Cadmium accumulation
  • Calcium influx
  • Half-maximal lethal concentration
  • Maximum velocity
  • Michaelis constant

ASJC Scopus subject areas

  • Physiology
  • Physiology (medical)

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