Castleman's disease in a 44-year-old male with neurofibromatosis and pheochromocytoma

H. Tom Stelfox, A. Keith Stewart, Dennis Bailey, David Harrison

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


A case of Castleman's disease in a patient with type I neurofibromatosis and pheochromocytoma is reported. The association of pheochromocytoma and neurofibromatosis is well documented, but uncommon. Castleman's disease has not been previously documented in a patient with neurofibromatosis or pheochromocytoma and may represent a previously unrecognized association of this disease. Castleman's disease is an interleukin-6 (IL-6) mediated B-cell proliferation. We postulate a relationship between pheochromocytoma IL-6 secretion and Castleman's disease. The relevant literature relating to this unusual case is reviewed.

Original languageEnglish (US)
Pages (from-to)551-556
Number of pages6
JournalLeukemia and Lymphoma
Issue number5-6
StatePublished - 1997


  • Castleman's disease
  • Neurofibromatosis
  • Pheochromocytoma

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research


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