TY - JOUR
T1 - Caspases and caspase inhibitors
AU - Villa, Pascal
AU - Kaufmann, Scott H.
AU - Earnshaw, William C.
PY - 1997/10
Y1 - 1997/10
N2 - Five years ago, little was known about mechanisms of apoptotic execution. Now, one class of cell-death gene, the cysteine aspartases (caspases) has come under intensive study, This review discusses the two classes of caspases, the reasons why humans may have so many caspase genes, the growing list of caspase substrates, and viral and pharmacological caspase inhibitors.
AB - Five years ago, little was known about mechanisms of apoptotic execution. Now, one class of cell-death gene, the cysteine aspartases (caspases) has come under intensive study, This review discusses the two classes of caspases, the reasons why humans may have so many caspase genes, the growing list of caspase substrates, and viral and pharmacological caspase inhibitors.
UR - http://www.scopus.com/inward/record.url?scp=0343990060&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0343990060&partnerID=8YFLogxK
U2 - 10.1016/S0968-0004(97)01107-9
DO - 10.1016/S0968-0004(97)01107-9
M3 - Review article
C2 - 9357314
AN - SCOPUS:0343990060
SN - 0968-0004
VL - 22
SP - 388
EP - 393
JO - Trends in biochemical sciences
JF - Trends in biochemical sciences
IS - 10
ER -