Carotid Intima-Media Thickness Testing by Non-Sonographer Clinicians: The Office Practice Assessment of Carotid Atherosclerosis Study

Claudia E. Korcarz, Alan T. Hirsch, Charles Bruce, Jeanne M. DeCara, Emile R. Mohler, Bryan Pogue, John Postley, Wendy S. Tzou, James H. Stein

Research output: Contribution to journalArticle

24 Scopus citations


Background: The purpose of this study was to determine whether a non-sonographer clinician (NSC) could obtain ultrasound images of the carotid artery, measure carotid intima-media thickness (CIMT), and identify findings indicating increased cardiovascular risk in an office setting. Methods: Eight NSCs from five sites were trained to use a handheld ultrasound device to screen the carotid arteries for plaques and to measure CIMT. Results: NSCs scanned 150 subjects who provided 900 images, of which 873 (97%) were interpretable. Differences between NSCs and the core laboratory were small (0.002 ± 0.004 mm) and bioequivalent (PTOST < 0.05) with a low coefficient of variation (3.9% ± 0.5%). There was ≥ 90% agreement on the presence of CIMT ≥ 75th percentile and ≥ 80% agreement on plaque presence. Conclusions: This is the first multicenter study to show that NSCs can obtain images of the carotid arteries using a handheld ultrasound device, accurately measure CIMT, and identify findings indicating increased cardiovascular risk.

Original languageEnglish (US)
Pages (from-to)117-122
Number of pages6
JournalJournal of the American Society of Echocardiography
Issue number2
StatePublished - Feb 1 2008


ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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