Carotid endarterectomy: Can we select surgical candidates at high risk for stroke and low risk for perioperative complications?

Giuseppe Lanzino, Daniel Couture, Alvaro Andreoli, Lee R. Guterman, L. Nelson Hopkins

Research output: Contribution to journalReview articlepeer-review

23 Scopus citations

Abstract

DESPITE EVIDENCE OF the efficacy of carotid endarterectomy from the large randomized multicenter trials completed in the 1990s, the physician who treats patients with carotid artery stenosis still is faced with a difficult management decision. More recently, subgroup analyses have been conducted of asymptomatic and symptomatic patients enrolled in these trials to identify clinical and radiological factors that increase the rates of morbidity and mortality associated with surgery, as well as those that increase the risk of stroke without surgery. Knowledge of these factors is important to recommend the best course of action for the individual patient. In this article, we summarize the conclusions of some of the subgroup analyses from the major carotid endarterectomy trials.

Original languageEnglish (US)
Pages (from-to)913-924
Number of pages12
JournalNeurosurgery
Volume49
Issue number4
DOIs
StatePublished - Jan 1 2001

Keywords

  • Carotid artery stenosis
  • Carotid endarterectomy
  • Outcome
  • Risk factors
  • Stroke

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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