Cardiovascular effects of microinjection of adenosine into the nucleus tractus solitarius

Robin A. Barraco, C. J. Janusz, Petra Marcela Casey, M. Parizon, P. A. Roberts

Research output: Contribution to journalArticle

73 Citations (Scopus)

Abstract

Rats were anesthetized with urethane and limited occipital craniotomy was conducted to expose the caudal medulla in the region of the obex. Microinjections of adenosine were made into the nucleus tractus solitarius and heart rate and blood pressure responses recorded. Adenosine produced dose-related decreases in blood pressure and heart rate. The data indicate that adenosine may play a neuromodulatory role in central cardiovascular control areas.

Original languageEnglish (US)
Pages (from-to)129-132
Number of pages4
JournalBrain Research Bulletin
Volume20
Issue number1
DOIs
StatePublished - 1988
Externally publishedYes

Fingerprint

Solitary Nucleus
Microinjections
Adenosine
Heart Rate
Blood Pressure
Craniotomy
Urethane

Keywords

  • Adenosine
  • Blood pressure
  • Heart rate
  • Nucleus tractus solitarius

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Cardiovascular effects of microinjection of adenosine into the nucleus tractus solitarius. / Barraco, Robin A.; Janusz, C. J.; Casey, Petra Marcela; Parizon, M.; Roberts, P. A.

In: Brain Research Bulletin, Vol. 20, No. 1, 1988, p. 129-132.

Research output: Contribution to journalArticle

Barraco, Robin A. ; Janusz, C. J. ; Casey, Petra Marcela ; Parizon, M. ; Roberts, P. A. / Cardiovascular effects of microinjection of adenosine into the nucleus tractus solitarius. In: Brain Research Bulletin. 1988 ; Vol. 20, No. 1. pp. 129-132.
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