TY - JOUR
T1 - Cardiovascular disease in women
T2 - Clinical perspectives
AU - Garcia, Mariana
AU - Mulvagh, Sharon L.
AU - Merz, C. Noel Bairey
AU - Buring, Julie E.
AU - Manson, Jo Ann E.
N1 - Publisher Copyright:
© 2016 American Heart Association, Inc.
PY - 2016/4/15
Y1 - 2016/4/15
N2 - Cardiovascular disease continues to be the leading cause of death among women in the United States, accounting for ≈1 of every 3 female deaths. Sex-specific data focused on cardiovascular disease have been increasing steadily, yet is not routinely collected nor translated into practice. This comprehensive review focuses on novel and unique aspects of cardiovascular health in women and sex differences as they relate to clinical practice in the prevention, diagnosis, and treatment of cardiovascular disease. This review also provides current approaches to the evaluation and treatment of acute coronary syndromes that are more prevalent in women, including myocardial infarction associated with nonobstructive coronary arteries, spontaneous coronary artery dissection, and stress-induced cardiomyopathy (Takotsubo Syndrome). Other cardiovascular disease entities with higher prevalence or unique considerations in women, such as heart failure with preserved ejection fraction, peripheral arterial disease, and abdominal aortic aneurysms, are also briefly reviewed. Finally, recommendations for cardiac rehabilitation are addressed.
AB - Cardiovascular disease continues to be the leading cause of death among women in the United States, accounting for ≈1 of every 3 female deaths. Sex-specific data focused on cardiovascular disease have been increasing steadily, yet is not routinely collected nor translated into practice. This comprehensive review focuses on novel and unique aspects of cardiovascular health in women and sex differences as they relate to clinical practice in the prevention, diagnosis, and treatment of cardiovascular disease. This review also provides current approaches to the evaluation and treatment of acute coronary syndromes that are more prevalent in women, including myocardial infarction associated with nonobstructive coronary arteries, spontaneous coronary artery dissection, and stress-induced cardiomyopathy (Takotsubo Syndrome). Other cardiovascular disease entities with higher prevalence or unique considerations in women, such as heart failure with preserved ejection fraction, peripheral arterial disease, and abdominal aortic aneurysms, are also briefly reviewed. Finally, recommendations for cardiac rehabilitation are addressed.
KW - acute coronary syndromes
KW - cardiovascular disease
KW - primary prevention
KW - risk factors
KW - women
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U2 - 10.1161/CIRCRESAHA.116.307547
DO - 10.1161/CIRCRESAHA.116.307547
M3 - Review article
C2 - 27081110
AN - SCOPUS:84963799420
SN - 0009-7330
VL - 118
SP - 1273
EP - 1293
JO - Circulation research
JF - Circulation research
IS - 8
ER -