Cardiorespiratory effects of inelastic chest wall restriction

Jordan D Miller, Kenneth C. Beck, Michael Joseph Joyner, A. Glenn Brice, Bruce David Johnson

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

We examined the effects of chest wall restriction (CWR) on cardiorespiratory function at rest and during exercise in healthy subjects in an attempt to approximate the cardiorespiratory interactions observed in clinical conditions that result in restrictive lung and/or chest wall changes and a reduced intrathoracic space. Canvas straps were applied around the thorax and abdomen so that vital capacity was reduced by >35%. Data were acquired at rest and during cycle ergometry at 25 and 45% of peak workloads. CWR elicited significant increases in the flow-resistive work performed on the lung (160%) and the gastric pressure-time integral (>400%) at the higher work-load, but it resulted in a decrease in the elastic work performed on the lung (56%) compared with control conditions. With CWR, heart rate increased and stroke volume (SV) fell, resulting in >10% fall in cardiac output at rest and during exercise at matched workloads (P < 0.05). Blood pressure and catecholamines were significantly elevated during CWR exercise conditions (P < 0.05). We conclude that CWR significantly impairs SV during exercise and that a compensatory increase in heart rate does not prevent a significant reduction in cardiac output. O 2 consumption appears to be maintained via increased extraction and a redistribution of blood flow via sympathetic activation.

Original languageEnglish (US)
Pages (from-to)2419-2428
Number of pages10
JournalJournal of Applied Physiology
Volume92
Issue number6
StatePublished - 2002

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Thoracic Wall
Workload
Exercise
Cardiac Output
Stroke Volume
Lung
Heart Rate
Ergometry
Vital Capacity
Abdomen
Catecholamines
Stomach
Healthy Volunteers
Thorax
Blood Pressure
Pressure

Keywords

  • Cardiac output
  • Exercise limitations
  • Metabolic reflexes
  • Work of breathing

ASJC Scopus subject areas

  • Physiology
  • Endocrinology
  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Cardiorespiratory effects of inelastic chest wall restriction. / Miller, Jordan D; Beck, Kenneth C.; Joyner, Michael Joseph; Glenn Brice, A.; Johnson, Bruce David.

In: Journal of Applied Physiology, Vol. 92, No. 6, 2002, p. 2419-2428.

Research output: Contribution to journalArticle

Miller, JD, Beck, KC, Joyner, MJ, Glenn Brice, A & Johnson, BD 2002, 'Cardiorespiratory effects of inelastic chest wall restriction', Journal of Applied Physiology, vol. 92, no. 6, pp. 2419-2428.
Miller, Jordan D ; Beck, Kenneth C. ; Joyner, Michael Joseph ; Glenn Brice, A. ; Johnson, Bruce David. / Cardiorespiratory effects of inelastic chest wall restriction. In: Journal of Applied Physiology. 2002 ; Vol. 92, No. 6. pp. 2419-2428.
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