Cardiopulmonary consequences of obstructive sleep apnea

Sean M. Caples, Tomas Kara, Virend Somers

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Ongoing research in obstructive sleep apnea (OSA) suggests strong associations with cardiopulmonary disorders. There is an abundance of studies describing physiological pathways in OSA that acutely impact the cardiovascular system. These mechanisms, if proven to carry over into the daytime hours, could form the basis for clinical disease. The challenge remains in disentangling these mechanistic processes from the many comorbid conditions often present in patients with OSA. Examples include male gender, obesity, and diabetes mellitus, all of which exert their own influence on the development of cardiopulmonary disease. This review discusses some of the physiological mechanisms associated with disordered breathing during sleep and explores putative cardiopulmonary disease associations.

Original languageEnglish (US)
Pages (from-to)25-32
Number of pages8
JournalSeminars in Respiratory and Critical Care Medicine
Volume26
Issue number1
DOIs
StatePublished - Feb 2005

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Obstructive Sleep Apnea
Sleep Apnea Syndromes
Cardiovascular System
Diabetes Mellitus
Obesity
Research

Keywords

  • Cardiovascular disease
  • Hypoventilation
  • Obesity
  • Obstructive sleep apnea
  • Sleep-disordered breathing

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine
  • Pulmonary and Respiratory Medicine
  • Critical Care

Cite this

Cardiopulmonary consequences of obstructive sleep apnea. / Caples, Sean M.; Kara, Tomas; Somers, Virend.

In: Seminars in Respiratory and Critical Care Medicine, Vol. 26, No. 1, 02.2005, p. 25-32.

Research output: Contribution to journalArticle

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