Cardiogenic motion of right lung parenchyma in anesthetized intact dogs

J. H. Wei, E. A. Hoffman, E. L. Ritman, E. H. Wood

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Cardiogenic motion of the right lung parenchyma (CGLM) was measured in six morphine-pentobarbital-anesthetized dogs (11-16 kg) under conditions of varying paced and spontaneous sinus heart rates. Motion of 1-mm-diameter percutaneously implanted radiopaque lung parenchymal markers were measured using a computer-based biplane video-roentgenographic assembly. Correlation of the amplitudes and phases of marker motions to the R wave of the electrocardiogram (ECG) were determined utilizing a modified fast Fourier transform algorithm. Of initial importance was the observation that CGLM was significantly greater than the variability of repeated measurements. The total amplitudes of motion of the markers (where A(t) = √(A(x) 2 + A(y) 2 + A(z) 2) and A(x), A(y), A(z) are the amplitudes of marker motion along the orthogonal X, Y, and Z body axes) in the right apical, cardiac, and diaphragmatic lobes were 0.025 ± 0.005 (SE), 0.046 ± 0.005, and 0.023 ± 0.025 cm, respectively, (P < 0.01, cardiac lobe vs. others). The total amplitude of motion observed in the cardiac lobe was equivalent to earlier observations of total amplitude (0.045 ± 0.004 cm) of marker motion in response to high frequency airway oscillation at a pump stroke volume of 22-26 ml. An analysis of the higher harmonics of marker oscillation suggested that the second harmonic of CGLM is also larger than the variability of our measurements.

Original languageEnglish (US)
Pages (from-to)384-391
Number of pages8
JournalJournal of Applied Physiology
Volume58
Issue number2
StatePublished - 1985

Fingerprint

Dogs
Lung
Fourier Analysis
Pentobarbital
Stroke Volume
Morphine
Electrocardiography
Heart Rate

ASJC Scopus subject areas

  • Endocrinology
  • Physiology
  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Wei, J. H., Hoffman, E. A., Ritman, E. L., & Wood, E. H. (1985). Cardiogenic motion of right lung parenchyma in anesthetized intact dogs. Journal of Applied Physiology, 58(2), 384-391.

Cardiogenic motion of right lung parenchyma in anesthetized intact dogs. / Wei, J. H.; Hoffman, E. A.; Ritman, E. L.; Wood, E. H.

In: Journal of Applied Physiology, Vol. 58, No. 2, 1985, p. 384-391.

Research output: Contribution to journalArticle

Wei, JH, Hoffman, EA, Ritman, EL & Wood, EH 1985, 'Cardiogenic motion of right lung parenchyma in anesthetized intact dogs', Journal of Applied Physiology, vol. 58, no. 2, pp. 384-391.
Wei, J. H. ; Hoffman, E. A. ; Ritman, E. L. ; Wood, E. H. / Cardiogenic motion of right lung parenchyma in anesthetized intact dogs. In: Journal of Applied Physiology. 1985 ; Vol. 58, No. 2. pp. 384-391.
@article{45005bef7e09405c9e5aa3d324eab05c,
title = "Cardiogenic motion of right lung parenchyma in anesthetized intact dogs",
abstract = "Cardiogenic motion of the right lung parenchyma (CGLM) was measured in six morphine-pentobarbital-anesthetized dogs (11-16 kg) under conditions of varying paced and spontaneous sinus heart rates. Motion of 1-mm-diameter percutaneously implanted radiopaque lung parenchymal markers were measured using a computer-based biplane video-roentgenographic assembly. Correlation of the amplitudes and phases of marker motions to the R wave of the electrocardiogram (ECG) were determined utilizing a modified fast Fourier transform algorithm. Of initial importance was the observation that CGLM was significantly greater than the variability of repeated measurements. The total amplitudes of motion of the markers (where A(t) = √(A(x) 2 + A(y) 2 + A(z) 2) and A(x), A(y), A(z) are the amplitudes of marker motion along the orthogonal X, Y, and Z body axes) in the right apical, cardiac, and diaphragmatic lobes were 0.025 ± 0.005 (SE), 0.046 ± 0.005, and 0.023 ± 0.025 cm, respectively, (P < 0.01, cardiac lobe vs. others). The total amplitude of motion observed in the cardiac lobe was equivalent to earlier observations of total amplitude (0.045 ± 0.004 cm) of marker motion in response to high frequency airway oscillation at a pump stroke volume of 22-26 ml. An analysis of the higher harmonics of marker oscillation suggested that the second harmonic of CGLM is also larger than the variability of our measurements.",
author = "Wei, {J. H.} and Hoffman, {E. A.} and Ritman, {E. L.} and Wood, {E. H.}",
year = "1985",
language = "English (US)",
volume = "58",
pages = "384--391",
journal = "Journal of Applied Physiology",
issn = "8750-7587",
publisher = "American Physiological Society",
number = "2",

}

TY - JOUR

T1 - Cardiogenic motion of right lung parenchyma in anesthetized intact dogs

AU - Wei, J. H.

AU - Hoffman, E. A.

AU - Ritman, E. L.

AU - Wood, E. H.

PY - 1985

Y1 - 1985

N2 - Cardiogenic motion of the right lung parenchyma (CGLM) was measured in six morphine-pentobarbital-anesthetized dogs (11-16 kg) under conditions of varying paced and spontaneous sinus heart rates. Motion of 1-mm-diameter percutaneously implanted radiopaque lung parenchymal markers were measured using a computer-based biplane video-roentgenographic assembly. Correlation of the amplitudes and phases of marker motions to the R wave of the electrocardiogram (ECG) were determined utilizing a modified fast Fourier transform algorithm. Of initial importance was the observation that CGLM was significantly greater than the variability of repeated measurements. The total amplitudes of motion of the markers (where A(t) = √(A(x) 2 + A(y) 2 + A(z) 2) and A(x), A(y), A(z) are the amplitudes of marker motion along the orthogonal X, Y, and Z body axes) in the right apical, cardiac, and diaphragmatic lobes were 0.025 ± 0.005 (SE), 0.046 ± 0.005, and 0.023 ± 0.025 cm, respectively, (P < 0.01, cardiac lobe vs. others). The total amplitude of motion observed in the cardiac lobe was equivalent to earlier observations of total amplitude (0.045 ± 0.004 cm) of marker motion in response to high frequency airway oscillation at a pump stroke volume of 22-26 ml. An analysis of the higher harmonics of marker oscillation suggested that the second harmonic of CGLM is also larger than the variability of our measurements.

AB - Cardiogenic motion of the right lung parenchyma (CGLM) was measured in six morphine-pentobarbital-anesthetized dogs (11-16 kg) under conditions of varying paced and spontaneous sinus heart rates. Motion of 1-mm-diameter percutaneously implanted radiopaque lung parenchymal markers were measured using a computer-based biplane video-roentgenographic assembly. Correlation of the amplitudes and phases of marker motions to the R wave of the electrocardiogram (ECG) were determined utilizing a modified fast Fourier transform algorithm. Of initial importance was the observation that CGLM was significantly greater than the variability of repeated measurements. The total amplitudes of motion of the markers (where A(t) = √(A(x) 2 + A(y) 2 + A(z) 2) and A(x), A(y), A(z) are the amplitudes of marker motion along the orthogonal X, Y, and Z body axes) in the right apical, cardiac, and diaphragmatic lobes were 0.025 ± 0.005 (SE), 0.046 ± 0.005, and 0.023 ± 0.025 cm, respectively, (P < 0.01, cardiac lobe vs. others). The total amplitude of motion observed in the cardiac lobe was equivalent to earlier observations of total amplitude (0.045 ± 0.004 cm) of marker motion in response to high frequency airway oscillation at a pump stroke volume of 22-26 ml. An analysis of the higher harmonics of marker oscillation suggested that the second harmonic of CGLM is also larger than the variability of our measurements.

UR - http://www.scopus.com/inward/record.url?scp=0021792044&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021792044&partnerID=8YFLogxK

M3 - Article

C2 - 3980346

AN - SCOPUS:0021792044

VL - 58

SP - 384

EP - 391

JO - Journal of Applied Physiology

JF - Journal of Applied Physiology

SN - 8750-7587

IS - 2

ER -