TY - JOUR
T1 - Cardiogenic motion of right lung parenchyma in anesthetized intact dogs
AU - Wei, J. H.
AU - Hoffman, E. A.
AU - Ritman, E. L.
AU - Wood, E. H.
PY - 1985
Y1 - 1985
N2 - Cardiogenic motion of the right lung parenchyma (CGLM) was measured in six morphine-pentobarbital-anesthetized dogs (11-16 kg) under conditions of varying paced and spontaneous sinus heart rates. Motion of 1-mm-diameter percutaneously implanted radiopaque lung parenchymal markers were measured using a computer-based biplane video-roentgenographic assembly. Correlation of the amplitudes and phases of marker motions to the R wave of the electrocardiogram (ECG) were determined utilizing a modified fast Fourier transform algorithm. Of initial importance was the observation that CGLM was significantly greater than the variability of repeated measurements. The total amplitudes of motion of the markers (where A(t) = √(A(x)2 + A(y)2 + A(z)2) and A(x), A(y), A(z) are the amplitudes of marker motion along the orthogonal X, Y, and Z body axes) in the right apical, cardiac, and diaphragmatic lobes were 0.025 ± 0.005 (SE), 0.046 ± 0.005, and 0.023 ± 0.025 cm, respectively, (P < 0.01, cardiac lobe vs. others). The total amplitude of motion observed in the cardiac lobe was equivalent to earlier observations of total amplitude (0.045 ± 0.004 cm) of marker motion in response to high frequency airway oscillation at a pump stroke volume of 22-26 ml. An analysis of the higher harmonics of marker oscillation suggested that the second harmonic of CGLM is also larger than the variability of our measurements.
AB - Cardiogenic motion of the right lung parenchyma (CGLM) was measured in six morphine-pentobarbital-anesthetized dogs (11-16 kg) under conditions of varying paced and spontaneous sinus heart rates. Motion of 1-mm-diameter percutaneously implanted radiopaque lung parenchymal markers were measured using a computer-based biplane video-roentgenographic assembly. Correlation of the amplitudes and phases of marker motions to the R wave of the electrocardiogram (ECG) were determined utilizing a modified fast Fourier transform algorithm. Of initial importance was the observation that CGLM was significantly greater than the variability of repeated measurements. The total amplitudes of motion of the markers (where A(t) = √(A(x)2 + A(y)2 + A(z)2) and A(x), A(y), A(z) are the amplitudes of marker motion along the orthogonal X, Y, and Z body axes) in the right apical, cardiac, and diaphragmatic lobes were 0.025 ± 0.005 (SE), 0.046 ± 0.005, and 0.023 ± 0.025 cm, respectively, (P < 0.01, cardiac lobe vs. others). The total amplitude of motion observed in the cardiac lobe was equivalent to earlier observations of total amplitude (0.045 ± 0.004 cm) of marker motion in response to high frequency airway oscillation at a pump stroke volume of 22-26 ml. An analysis of the higher harmonics of marker oscillation suggested that the second harmonic of CGLM is also larger than the variability of our measurements.
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U2 - 10.1152/jappl.1985.58.2.384
DO - 10.1152/jappl.1985.58.2.384
M3 - Article
C2 - 3980346
AN - SCOPUS:0021792044
SN - 8750-7587
VL - 58
SP - 384
EP - 391
JO - Journal of applied physiology
JF - Journal of applied physiology
IS - 2
ER -