Cardiac resynchronization therapy has been proven to be clearly beneficial for patients with heart failure, a prolonged QRS duration, and a left ventricular ejection fraction ≤35%. Ejection fraction cutoff, however, is arbitrary and very likely excludes many patients who could benefit from cardiac resynchronization. This article describes the major detrimental effects of left bundle branch block and summarizes the data regarding the potential beneficial effects of cardiac resynchronization in patients with a left ventricular ejection fraction greater than 35%.
- Cardiac resynchronization therapy
- Heart failure with preserved ejection fraction
- Heart failure with reduced ejection fraction
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Physiology (medical)