Cardiac papillary fibroelastoma: A treatable cause of transient ischemic attack and ischemic stroke detected by transesophageal echocardiography

Robert D Jr. Brown, B. K. Khandheria, W. D. Edwards

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

Transesophageal echocardiography (TEE) is used frequently in patients with cerebrovascular ischemia. On TEE, a typical appearance of a cardiac fibroelastoma is that of a pedunculated, mobile mass attached to a leaflet of a valve. Surgical excision of the lesion may lead to resolution of the symptoms and prevent further cerebrovascular ischemic events; valve replacement is seldom necessary. Herein we describe three patients with cerebral or ocular ischemia in whom histologic study confirmed a cardiac papillary fibroelastoma after initial detection by TEE. Cardiac papillary fibroelastomas should be considered in the differential diagnosis of transient ischemic attack and stroke, even in cases of recurrent events in the same vascular distribution. Although the use of echocardiography in the evaluation of stroke and transient ischemic attack is controversial, TEE must be considered in patients in whom the cause of cerebrovascular ischemia is unclear after noninvasive neurovascular studies or transthoracic echocardiography, even if the patient's cardiac history and the findings on physical examination are normal.

Original languageEnglish (US)
Pages (from-to)863-868
Number of pages6
JournalMayo Clinic Proceedings
Volume70
Issue number9
StatePublished - 1995

Fingerprint

Transient Ischemic Attack
Transesophageal Echocardiography
Stroke
Ischemia
Echocardiography
Physical Examination
Blood Vessels
Differential Diagnosis
History

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Cardiac papillary fibroelastoma : A treatable cause of transient ischemic attack and ischemic stroke detected by transesophageal echocardiography. / Brown, Robert D Jr.; Khandheria, B. K.; Edwards, W. D.

In: Mayo Clinic Proceedings, Vol. 70, No. 9, 1995, p. 863-868.

Research output: Contribution to journalArticle

@article{e01eebc78c654cc28d1a517c18d9ae8b,
title = "Cardiac papillary fibroelastoma: A treatable cause of transient ischemic attack and ischemic stroke detected by transesophageal echocardiography",
abstract = "Transesophageal echocardiography (TEE) is used frequently in patients with cerebrovascular ischemia. On TEE, a typical appearance of a cardiac fibroelastoma is that of a pedunculated, mobile mass attached to a leaflet of a valve. Surgical excision of the lesion may lead to resolution of the symptoms and prevent further cerebrovascular ischemic events; valve replacement is seldom necessary. Herein we describe three patients with cerebral or ocular ischemia in whom histologic study confirmed a cardiac papillary fibroelastoma after initial detection by TEE. Cardiac papillary fibroelastomas should be considered in the differential diagnosis of transient ischemic attack and stroke, even in cases of recurrent events in the same vascular distribution. Although the use of echocardiography in the evaluation of stroke and transient ischemic attack is controversial, TEE must be considered in patients in whom the cause of cerebrovascular ischemia is unclear after noninvasive neurovascular studies or transthoracic echocardiography, even if the patient's cardiac history and the findings on physical examination are normal.",
author = "Brown, {Robert D Jr.} and Khandheria, {B. K.} and Edwards, {W. D.}",
year = "1995",
language = "English (US)",
volume = "70",
pages = "863--868",
journal = "Mayo Clinic Proceedings",
issn = "0025-6196",
publisher = "Elsevier Science",
number = "9",

}

TY - JOUR

T1 - Cardiac papillary fibroelastoma

T2 - A treatable cause of transient ischemic attack and ischemic stroke detected by transesophageal echocardiography

AU - Brown, Robert D Jr.

AU - Khandheria, B. K.

AU - Edwards, W. D.

PY - 1995

Y1 - 1995

N2 - Transesophageal echocardiography (TEE) is used frequently in patients with cerebrovascular ischemia. On TEE, a typical appearance of a cardiac fibroelastoma is that of a pedunculated, mobile mass attached to a leaflet of a valve. Surgical excision of the lesion may lead to resolution of the symptoms and prevent further cerebrovascular ischemic events; valve replacement is seldom necessary. Herein we describe three patients with cerebral or ocular ischemia in whom histologic study confirmed a cardiac papillary fibroelastoma after initial detection by TEE. Cardiac papillary fibroelastomas should be considered in the differential diagnosis of transient ischemic attack and stroke, even in cases of recurrent events in the same vascular distribution. Although the use of echocardiography in the evaluation of stroke and transient ischemic attack is controversial, TEE must be considered in patients in whom the cause of cerebrovascular ischemia is unclear after noninvasive neurovascular studies or transthoracic echocardiography, even if the patient's cardiac history and the findings on physical examination are normal.

AB - Transesophageal echocardiography (TEE) is used frequently in patients with cerebrovascular ischemia. On TEE, a typical appearance of a cardiac fibroelastoma is that of a pedunculated, mobile mass attached to a leaflet of a valve. Surgical excision of the lesion may lead to resolution of the symptoms and prevent further cerebrovascular ischemic events; valve replacement is seldom necessary. Herein we describe three patients with cerebral or ocular ischemia in whom histologic study confirmed a cardiac papillary fibroelastoma after initial detection by TEE. Cardiac papillary fibroelastomas should be considered in the differential diagnosis of transient ischemic attack and stroke, even in cases of recurrent events in the same vascular distribution. Although the use of echocardiography in the evaluation of stroke and transient ischemic attack is controversial, TEE must be considered in patients in whom the cause of cerebrovascular ischemia is unclear after noninvasive neurovascular studies or transthoracic echocardiography, even if the patient's cardiac history and the findings on physical examination are normal.

UR - http://www.scopus.com/inward/record.url?scp=0029112866&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029112866&partnerID=8YFLogxK

M3 - Article

C2 - 7643640

AN - SCOPUS:0029112866

VL - 70

SP - 863

EP - 868

JO - Mayo Clinic Proceedings

JF - Mayo Clinic Proceedings

SN - 0025-6196

IS - 9

ER -