TY - JOUR
T1 - Cardiac chloride channels
AU - Ackerman, Michael J.
AU - Clapham, David E.
N1 - Funding Information:
The authors thank Drs. Markus Paul-michl and Lisa Stehno-Bittel for their reading of the manuscript. D.E.C. is supported by National Institutes of Health grant NM DK44025 and is an Established Investigator of the American Heart Association.
PY - 1993
Y1 - 1993
N2 - Cardiac chloride channels, once largely ignored, are the subject of renewed exploration. Consequently, their molecular identities and electrophysiologic properties are being defined and have revealed a distinct family of ionic channels capable of uniquely influencing the cardiac action potential. Targeting these channel proteins may provide novel antiarrhythmic strategies.
AB - Cardiac chloride channels, once largely ignored, are the subject of renewed exploration. Consequently, their molecular identities and electrophysiologic properties are being defined and have revealed a distinct family of ionic channels capable of uniquely influencing the cardiac action potential. Targeting these channel proteins may provide novel antiarrhythmic strategies.
UR - http://www.scopus.com/inward/record.url?scp=0027456578&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0027456578&partnerID=8YFLogxK
U2 - 10.1016/1050-1738(93)90024-Z
DO - 10.1016/1050-1738(93)90024-Z
M3 - Short survey
C2 - 21244967
AN - SCOPUS:0027456578
SN - 1050-1738
VL - 3
SP - 23
EP - 28
JO - Trends in cardiovascular medicine
JF - Trends in cardiovascular medicine
IS - 1
ER -