Carbapenem- and colistin-resistant Enterobacter cloacae from Delta, Colorado, in 2015

Andrew P. Norgan, Jarred M. Freese, Patricia M. Tuin, Scott A. Cunningham, Patricio R. Jeraldo, Robin Patel

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

Resistance to carbapenems in Enterobacteriaceae is a clinical problem of growing significance. Difficulty in treating multidrugresistant Gram-negative organisms with conventional antibiotics has led to a renewed and increasing use of polymyxin compounds, such as colistin. Here, we report the isolation of carbapenem- and colistin-resistant Enterobacter cloacae from a polymicrobial lower extremity wound in an ambulatory patient. Whole-genome sequencing demonstrated the presence of chromosomal blaIMI-1 and blaAmpC, as well as numerous efflux pump genes.

Original languageEnglish (US)
Pages (from-to)3141-3144
Number of pages4
JournalAntimicrobial Agents and Chemotherapy
Volume60
Issue number5
DOIs
StatePublished - May 2016

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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