Carbapenem- and colistin-resistant Enterobacter cloacae from Delta, Colorado, in 2015

Andrew P. Norgan; Jarred M. Freese; Patricia M. Tuin; Scott A. Cunningham; Patricio R. Jeraldo; Robin Patel

doi:10.1128/AAC.03055-15

Carbapenem- and colistin-resistant Enterobacter cloacae from Delta, Colorado, in 2015

Andrew P. Norgan, Jarred M. Freese, Patricia M. Tuin, Scott A. Cunningham, Patricio R. Jeraldo, Robin Patel

Laboratory Medicine and Pathology

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Resistance to carbapenems in Enterobacteriaceae is a clinical problem of growing significance. Difficulty in treating multidrugresistant Gram-negative organisms with conventional antibiotics has led to a renewed and increasing use of polymyxin compounds, such as colistin. Here, we report the isolation of carbapenem- and colistin-resistant Enterobacter cloacae from a polymicrobial lower extremity wound in an ambulatory patient. Whole-genome sequencing demonstrated the presence of chromosomal bla_IMI-1 and bla_AmpC, as well as numerous efflux pump genes.

Original language	English (US)
Pages (from-to)	3141-3144
Number of pages	4
Journal	Antimicrobial Agents and Chemotherapy
Volume	60
Issue number	5
DOIs	https://doi.org/10.1128/AAC.03055-15
State	Published - May 2016

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)
Infectious Diseases

Access to Document

10.1128/AAC.03055-15

Cite this

@article{cb53b32a71cc43c19890121b2c21ee74,

title = "Carbapenem- and colistin-resistant Enterobacter cloacae from Delta, Colorado, in 2015",

abstract = "Resistance to carbapenems in Enterobacteriaceae is a clinical problem of growing significance. Difficulty in treating multidrugresistant Gram-negative organisms with conventional antibiotics has led to a renewed and increasing use of polymyxin compounds, such as colistin. Here, we report the isolation of carbapenem- and colistin-resistant Enterobacter cloacae from a polymicrobial lower extremity wound in an ambulatory patient. Whole-genome sequencing demonstrated the presence of chromosomal blaIMI-1 and blaAmpC, as well as numerous efflux pump genes.",

author = "Norgan, {Andrew P.} and Freese, {Jarred M.} and Tuin, {Patricia M.} and Cunningham, {Scott A.} and Jeraldo, {Patricio R.} and Robin Patel",

year = "2016",

month = may,

doi = "10.1128/AAC.03055-15",

language = "English (US)",

volume = "60",

pages = "3141--3144",

journal = "Antimicrobial Agents and Chemotherapy",

issn = "0066-4804",

publisher = "American Society for Microbiology",

number = "5",

}

TY - JOUR

T1 - Carbapenem- and colistin-resistant Enterobacter cloacae from Delta, Colorado, in 2015

AU - Norgan, Andrew P.

AU - Freese, Jarred M.

AU - Tuin, Patricia M.

AU - Cunningham, Scott A.

AU - Jeraldo, Patricio R.

AU - Patel, Robin

PY - 2016/5

Y1 - 2016/5

N2 - Resistance to carbapenems in Enterobacteriaceae is a clinical problem of growing significance. Difficulty in treating multidrugresistant Gram-negative organisms with conventional antibiotics has led to a renewed and increasing use of polymyxin compounds, such as colistin. Here, we report the isolation of carbapenem- and colistin-resistant Enterobacter cloacae from a polymicrobial lower extremity wound in an ambulatory patient. Whole-genome sequencing demonstrated the presence of chromosomal blaIMI-1 and blaAmpC, as well as numerous efflux pump genes.

AB - Resistance to carbapenems in Enterobacteriaceae is a clinical problem of growing significance. Difficulty in treating multidrugresistant Gram-negative organisms with conventional antibiotics has led to a renewed and increasing use of polymyxin compounds, such as colistin. Here, we report the isolation of carbapenem- and colistin-resistant Enterobacter cloacae from a polymicrobial lower extremity wound in an ambulatory patient. Whole-genome sequencing demonstrated the presence of chromosomal blaIMI-1 and blaAmpC, as well as numerous efflux pump genes.

UR - http://www.scopus.com/inward/record.url?scp=84964909238&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84964909238&partnerID=8YFLogxK

U2 - 10.1128/AAC.03055-15

DO - 10.1128/AAC.03055-15

M3 - Article

C2 - 26883705

AN - SCOPUS:84964909238

SN - 0066-4804

VL - 60

SP - 3141

EP - 3144

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

IS - 5

ER -

Carbapenem- and colistin-resistant Enterobacter cloacae from Delta, Colorado, in 2015

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this