Capsule endoscopy in suspected small bowel Crohn's disease

Economic impact of disease diagnosis and treatment

Jonathan A Leighton, Ian M. Gralnek, Randel E. Richner, Michael J. Lacey, Frank J. Papatheofanis

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

AIM: To model clinical and economic benefits of capsule endoscopy (CE) compared to ileo-colonoscopy and small bowel follow-through (SBFT) for evaluation of suspected Crohn's disease (CD). METHODS: Using decision analytic modeling, total and yearly costs of diagnostic work-up for suspected CD were calculated, including procedure-related adverse events, hospitalizations, office visits, and medications. The model compared CE to SBFT following ileo-colonoscopy and secondarily compared CE to SBFT for initial evaluation. RESULTS: Aggregate charges for newly diagnosed, medically managed patients are approximately $8295. Patients requiring aggressive medical management costs are $29 508; requiring hospitalization, $49 074. At sensitivity > 98.7% and specificity of > 86.4%, CE is less costly than SBFT. CONCLUSION: Costs of CE for diagnostic evaluation of suspected CD is comparable to SBFT and may be used immediately following ileo-colonoscopy.

Original languageEnglish (US)
Pages (from-to)5685-5692
Number of pages8
JournalWorld Journal of Gastroenterology
Volume15
Issue number45
DOIs
StatePublished - Dec 7 2009

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Capsule Endoscopy
Crohn Disease
Economics
Colonoscopy
Costs and Cost Analysis
Hospitalization
Economic Models
Therapeutics
Office Visits
Decision Support Techniques

Keywords

  • Capsule endoscopy
  • Costs
  • Crohn's disease
  • Disease management

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Capsule endoscopy in suspected small bowel Crohn's disease : Economic impact of disease diagnosis and treatment. / Leighton, Jonathan A; Gralnek, Ian M.; Richner, Randel E.; Lacey, Michael J.; Papatheofanis, Frank J.

In: World Journal of Gastroenterology, Vol. 15, No. 45, 07.12.2009, p. 5685-5692.

Research output: Contribution to journalArticle

Leighton, Jonathan A ; Gralnek, Ian M. ; Richner, Randel E. ; Lacey, Michael J. ; Papatheofanis, Frank J. / Capsule endoscopy in suspected small bowel Crohn's disease : Economic impact of disease diagnosis and treatment. In: World Journal of Gastroenterology. 2009 ; Vol. 15, No. 45. pp. 5685-5692.
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