Cancer Nanotechnology: Emerging role of gold nanoconjugates

Rachel A. Kudgus, Resham Bhattacharya, Priyabrata Mukherjee

Research output: Contribution to journalReview article

31 Scopus citations

Abstract

Over the last few decades, the study of nanotechnology has grown exponentially. Nanotechnology bridges science, engineeringand technology; it continues to expand in definition as well as practice. One sub-set of nanotechnology is bionanotechnology,this will be the focus of this review. Currently, bionanotechnology is being studied and exploited for utility within medicinal imaging,diagnosis and therapy in regard to cancer. Cancer is a world-wide health problem and the implication rate as well as the death rateincrease year to year. However promising work is being done with gold nanoparticles for detection, diagnosis and targeted drug deliverytherapy. Gold nanoparticles can be synthesized in various shapes and sizes, which directly correlates to the color; they can also bemanipulated to carry various antibody, protein, plasmid, DNA or small molecule drug. Herein we summarize some of the very influentialresearch being done in the field of Cancer Nanotechnology with an emphasis on gold nanoparticles.

Original languageEnglish (US)
Pages (from-to)965-973
Number of pages9
JournalAnti-Cancer Agents in Medicinal Chemistry
Volume11
Issue number10
DOIs
StatePublished - Dec 2011

Keywords

  • Cancer
  • Gold
  • Nanoparticles
  • Targeted drug delivery

ASJC Scopus subject areas

  • Molecular Medicine
  • Pharmacology
  • Cancer Research

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