Cancer immunotherapy in patients with preexisting inflammatory arthritis

Uma Thanarajasingam; Noha Abdel-Wahab

doi:10.1007/978-3-030-56824-5_12

Cancer immunotherapy in patients with preexisting inflammatory arthritis

Uma Thanarajasingam, Noha Abdel-Wahab

Rheumatology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

This chapter focuses on patients with a preexisting inflammatory arthritis subsequently treated by immune checkpoint inhibitor (ICI) therapy for malignancy. We summarize the available epidemiologic and pathologic studies involving this subgroup of patients. An illustrative case of a patient with preexisting rheumatoid arthritis exposed to ICI for melanoma and followed longitudinally is presented in detail to highlight the clinical course and management challenges faced when caring for these patients.

Original language	English (US)
Title of host publication	Rheumatic Diseases and Syndromes Induced by Cancer Immunotherapy
Subtitle of host publication	A Handbook for Diagnosis and Management
Publisher	Springer International Publishing
Pages	273-291
Number of pages	19
ISBN (Electronic)	9783030568245
ISBN (Print)	9783030568238
DOIs	https://doi.org/10.1007/978-3-030-56824-5_12
State	Published - Feb 16 2021

Keywords

Immune checkpoint inhibitors
Immune-related adverse events
Inflammatory arthritis
Preexisting rheumatic diseases

ASJC Scopus subject areas

Medicine(all)
Immunology and Microbiology(all)

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10.1007/978-3-030-56824-5_12

Cite this

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AB - This chapter focuses on patients with a preexisting inflammatory arthritis subsequently treated by immune checkpoint inhibitor (ICI) therapy for malignancy. We summarize the available epidemiologic and pathologic studies involving this subgroup of patients. An illustrative case of a patient with preexisting rheumatoid arthritis exposed to ICI for melanoma and followed longitudinally is presented in detail to highlight the clinical course and management challenges faced when caring for these patients.

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Cancer immunotherapy in patients with preexisting inflammatory arthritis

Abstract

Keywords

ASJC Scopus subject areas

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