Can anatomical left ventricular mass be estimated reliably by M-mode echocardiography? A clinicopathological study of ninety-three patients

T. C. Bachenberg, C. Shub, A. J. Hauck, W. D. Edwards

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

To evaluate the accuracy of M-mode echocardiography in the assessment of left ventricular mass, we compared various echocardiography-derived regression equations for left ventricular mass to post-mortem left ventricular weights in 93 patients (mean age 68 ± 11 years) who had autopsy within 30 days of technically adequate two-dimensional guided M-mode echocardiography and who had normal left ventricular shape. The left ventricle was enlarged in 36 patients (39%) and was involved by chronic ischemic disease in 48 patients (52%). Only a modest correlation was found between M-mode echocardiography and anatomical left ventricular mass (range of correlation coefficients, 0.58 to 0.67). Each echocardiographic formula demonstrated increasing deviations as left ventricular mass increased. A previously suggested correction formula lessened overestimation, but considerable data dispersion remained. Regional wall-motion abnormalities, present in 22%, did not affect the correlation. We conclude that M-mode echocardiography, performed with standard methods, does not reliably estimate anatomical left ventricular mass, especially in patients with large hearts.

Original languageEnglish (US)
Pages (from-to)9-15
Number of pages7
JournalEchocardiography
Volume8
Issue number1
StatePublished - 1991

Fingerprint

Echocardiography
Heart Ventricles
Autopsy
Chronic Disease
Weights and Measures

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging

Cite this

Can anatomical left ventricular mass be estimated reliably by M-mode echocardiography? A clinicopathological study of ninety-three patients. / Bachenberg, T. C.; Shub, C.; Hauck, A. J.; Edwards, W. D.

In: Echocardiography, Vol. 8, No. 1, 1991, p. 9-15.

Research output: Contribution to journalArticle

@article{0f6fc89b7eca48e39ef7755d7e5eb251,
title = "Can anatomical left ventricular mass be estimated reliably by M-mode echocardiography? A clinicopathological study of ninety-three patients",
abstract = "To evaluate the accuracy of M-mode echocardiography in the assessment of left ventricular mass, we compared various echocardiography-derived regression equations for left ventricular mass to post-mortem left ventricular weights in 93 patients (mean age 68 ± 11 years) who had autopsy within 30 days of technically adequate two-dimensional guided M-mode echocardiography and who had normal left ventricular shape. The left ventricle was enlarged in 36 patients (39{\%}) and was involved by chronic ischemic disease in 48 patients (52{\%}). Only a modest correlation was found between M-mode echocardiography and anatomical left ventricular mass (range of correlation coefficients, 0.58 to 0.67). Each echocardiographic formula demonstrated increasing deviations as left ventricular mass increased. A previously suggested correction formula lessened overestimation, but considerable data dispersion remained. Regional wall-motion abnormalities, present in 22{\%}, did not affect the correlation. We conclude that M-mode echocardiography, performed with standard methods, does not reliably estimate anatomical left ventricular mass, especially in patients with large hearts.",
author = "Bachenberg, {T. C.} and C. Shub and Hauck, {A. J.} and Edwards, {W. D.}",
year = "1991",
language = "English (US)",
volume = "8",
pages = "9--15",
journal = "Echocardiography",
issn = "0742-2822",
publisher = "Wiley-Blackwell",
number = "1",

}

TY - JOUR

T1 - Can anatomical left ventricular mass be estimated reliably by M-mode echocardiography? A clinicopathological study of ninety-three patients

AU - Bachenberg, T. C.

AU - Shub, C.

AU - Hauck, A. J.

AU - Edwards, W. D.

PY - 1991

Y1 - 1991

N2 - To evaluate the accuracy of M-mode echocardiography in the assessment of left ventricular mass, we compared various echocardiography-derived regression equations for left ventricular mass to post-mortem left ventricular weights in 93 patients (mean age 68 ± 11 years) who had autopsy within 30 days of technically adequate two-dimensional guided M-mode echocardiography and who had normal left ventricular shape. The left ventricle was enlarged in 36 patients (39%) and was involved by chronic ischemic disease in 48 patients (52%). Only a modest correlation was found between M-mode echocardiography and anatomical left ventricular mass (range of correlation coefficients, 0.58 to 0.67). Each echocardiographic formula demonstrated increasing deviations as left ventricular mass increased. A previously suggested correction formula lessened overestimation, but considerable data dispersion remained. Regional wall-motion abnormalities, present in 22%, did not affect the correlation. We conclude that M-mode echocardiography, performed with standard methods, does not reliably estimate anatomical left ventricular mass, especially in patients with large hearts.

AB - To evaluate the accuracy of M-mode echocardiography in the assessment of left ventricular mass, we compared various echocardiography-derived regression equations for left ventricular mass to post-mortem left ventricular weights in 93 patients (mean age 68 ± 11 years) who had autopsy within 30 days of technically adequate two-dimensional guided M-mode echocardiography and who had normal left ventricular shape. The left ventricle was enlarged in 36 patients (39%) and was involved by chronic ischemic disease in 48 patients (52%). Only a modest correlation was found between M-mode echocardiography and anatomical left ventricular mass (range of correlation coefficients, 0.58 to 0.67). Each echocardiographic formula demonstrated increasing deviations as left ventricular mass increased. A previously suggested correction formula lessened overestimation, but considerable data dispersion remained. Regional wall-motion abnormalities, present in 22%, did not affect the correlation. We conclude that M-mode echocardiography, performed with standard methods, does not reliably estimate anatomical left ventricular mass, especially in patients with large hearts.

UR - http://www.scopus.com/inward/record.url?scp=0026008078&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026008078&partnerID=8YFLogxK

M3 - Article

VL - 8

SP - 9

EP - 15

JO - Echocardiography

JF - Echocardiography

SN - 0742-2822

IS - 1

ER -