Calming Neurons with a Microglial Touch

Kaushik Sharma; Long Jun Wu; Ukpong B. Eyo

doi:10.1016/j.tins.2020.01.008

Calming Neurons with a Microglial Touch

Kaushik Sharma, Long Jun Wu, Ukpong B. Eyo

Neurology

Research output: Contribution to journal › Short survey › peer-review

2 Scopus citations

Abstract

In vivo two-photon imaging of microglia in the intact brain has revealed that microglia constantly survey neuronal soma. Research over the past decade and a recent paper by Cserép et al. published in Science are now uncovering the nature, mechanisms, and consequences of these interactions in health and injury.

Original language	English (US)
Pages (from-to)	197-199
Number of pages	3
Journal	Trends in neurosciences
Volume	43
Issue number	4
DOIs	https://doi.org/10.1016/j.tins.2020.01.008
State	Published - Apr 2020

Keywords

Kv2.1
P2Y12
microglia
neuronal activity
neuroprotection

ASJC Scopus subject areas

Neuroscience(all)

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10.1016/j.tins.2020.01.008

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@article{38da748342f34c4abc849e12268ba904,

title = "Calming Neurons with a Microglial Touch",

abstract = "In vivo two-photon imaging of microglia in the intact brain has revealed that microglia constantly survey neuronal soma. Research over the past decade and a recent paper by Cser{\'e}p et al. published in Science are now uncovering the nature, mechanisms, and consequences of these interactions in health and injury.",

keywords = "Kv2.1, P2Y12, microglia, neuronal activity, neuroprotection",

author = "Kaushik Sharma and Wu, {Long Jun} and Eyo, {Ukpong B.}",

note = "Funding Information: We thank members of the laboratory of U.B.E. for their contributions in discussion of this manuscript. Our work is supported by grants from the National Institutes of Health ( K22NS104392 to U.B.E. and R01NS088627 to L-J.W.). Publisher Copyright: {\textcopyright} 2020",

year = "2020",

month = apr,

doi = "10.1016/j.tins.2020.01.008",

language = "English (US)",

volume = "43",

pages = "197--199",

journal = "Trends in Neurosciences",

issn = "0378-5912",

publisher = "Elsevier Limited",

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}

TY - JOUR

T1 - Calming Neurons with a Microglial Touch

AU - Sharma, Kaushik

AU - Wu, Long Jun

AU - Eyo, Ukpong B.

N1 - Funding Information: We thank members of the laboratory of U.B.E. for their contributions in discussion of this manuscript. Our work is supported by grants from the National Institutes of Health ( K22NS104392 to U.B.E. and R01NS088627 to L-J.W.). Publisher Copyright: © 2020

PY - 2020/4

Y1 - 2020/4

N2 - In vivo two-photon imaging of microglia in the intact brain has revealed that microglia constantly survey neuronal soma. Research over the past decade and a recent paper by Cserép et al. published in Science are now uncovering the nature, mechanisms, and consequences of these interactions in health and injury.

AB - In vivo two-photon imaging of microglia in the intact brain has revealed that microglia constantly survey neuronal soma. Research over the past decade and a recent paper by Cserép et al. published in Science are now uncovering the nature, mechanisms, and consequences of these interactions in health and injury.

KW - Kv2.1

KW - P2Y12

KW - microglia

KW - neuronal activity

KW - neuroprotection

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UR - http://www.scopus.com/inward/citedby.url?scp=85079393722&partnerID=8YFLogxK

U2 - 10.1016/j.tins.2020.01.008

DO - 10.1016/j.tins.2020.01.008

M3 - Short survey

C2 - 32209451

AN - SCOPUS:85079393722

SN - 0378-5912

VL - 43

SP - 197

EP - 199

JO - Trends in Neurosciences

JF - Trends in Neurosciences

IS - 4

ER -

Calming Neurons with a Microglial Touch

Abstract

Keywords

ASJC Scopus subject areas

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