Calcium, magnesium, and phosphorus metabolism in dogs given intravenous triacetin

J. W. Bailey, H. Heath, J. M. Miles

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Previous studies suggested that acetate in parenteral solutions may adversely affect mineral metabolism by causing sequestration of inorganic phosphate and calcium in the liver. In this study, triacetin, a short-chain triglyceride of acetate and a potential parenteral nutrient, was infused for 3 h at an isocaloric rate in mongrel dogs (n = 6) to test its effects on serum phosphorus, calcium, and magnesium metabolism. There was no change in serum P or Ca. The serum Mg concentration decreased from 0.7 ± 0.03 to 0.57 ± 0.03 mmol/L (p < 0.001) by 90 min and remained at this level for the remainder of the study. The triacetin infusion did not influence fractional urinary Mg excretion; thus, the decrease in serum Mg was likely because of an increase in cellular transport of this cation. A short-chain triglyceride administered to dogs at a rate approximating resting energy expenditure has no demonstrable adverse effects on mineral metabolism.

Original languageEnglish (US)
Pages (from-to)385-388
Number of pages4
JournalAmerican Journal of Clinical Nutrition
Volume49
Issue number2
StatePublished - 1989

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Triacetin
triacetin
mineral metabolism
Phosphorus
Magnesium
magnesium
triacylglycerols
acetates
Dogs
Calcium
calcium
phosphorus
resting energy expenditure
metabolism
dogs
Serum
Minerals
cations
Triglycerides
Acetates

ASJC Scopus subject areas

  • Food Science
  • Medicine (miscellaneous)

Cite this

Calcium, magnesium, and phosphorus metabolism in dogs given intravenous triacetin. / Bailey, J. W.; Heath, H.; Miles, J. M.

In: American Journal of Clinical Nutrition, Vol. 49, No. 2, 1989, p. 385-388.

Research output: Contribution to journalArticle

Bailey, J. W. ; Heath, H. ; Miles, J. M. / Calcium, magnesium, and phosphorus metabolism in dogs given intravenous triacetin. In: American Journal of Clinical Nutrition. 1989 ; Vol. 49, No. 2. pp. 385-388.
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