Abstract
Computer-aided diagnosis (CAD) systems must show sufficient versatility to produce robust analysis on a large variety of data. In the case of colonography, CAD has not been designed to cope with the presence of stool, although labeling the stool with high contrast agents replaces the use of laxatives and reduces the patient discomfort. This procedure introduces additional challenges for the diagnosis, such as poorly tagged stool, stool sticking to colonic walls, and heterogeneous stool (tagged stool mixed with air or untagged stool). Our study proposes a robust algorithm for heterogeneous stool removal to be employed as a preprocessing module for CAD systems in colonic cancer detection. Colonoscopy data are automatically cleansed of residual stool to enhance the polyp appearance for improved diagnosis. The algorithm uses expectationmaximization, quadratic regression, level sets and minimum variance. Results show stool removal accuracy on polyps which are partially or fully covered by stool. The results are robust on stool lining and large pools of heterogeneous and weakly-tagged stool. The automatic detection of colon polyps using our CAD system on cathartic-free data improves considerably with the addition of the automatic stool removal module from 74% to 86% true positive (TP) rate at 6.4 false positives (FP)/case.
| Original language | English (US) |
|---|---|
| Title of host publication | Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology" |
| Pages | 2996-2999 |
| Number of pages | 4 |
| State | Published - 2008 |
| Event | 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - Vancouver, BC, Canada Duration: Aug 20 2008 → Aug 25 2008 |
Other
| Other | 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 |
|---|---|
| Country | Canada |
| City | Vancouver, BC |
| Period | 8/20/08 → 8/25/08 |
Fingerprint
ASJC Scopus subject areas
- Computer Vision and Pattern Recognition
- Signal Processing
- Biomedical Engineering
- Health Informatics
Cite this
CAD of colon cancer on CT colonography cases without cathartic bowel preparation. / Linguraru, Marius George; Zhao, Shan; Van Uitert, Robert L.; Liu, Jiamin; Fletcher, Joel Garland; Manduca, Armando; Summers, Ronald M.
Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology". 2008. p. 2996-2999 4649833.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - CAD of colon cancer on CT colonography cases without cathartic bowel preparation
AU - Linguraru, Marius George
AU - Zhao, Shan
AU - Van Uitert, Robert L.
AU - Liu, Jiamin
AU - Fletcher, Joel Garland
AU - Manduca, Armando
AU - Summers, Ronald M.
PY - 2008
Y1 - 2008
N2 - Computer-aided diagnosis (CAD) systems must show sufficient versatility to produce robust analysis on a large variety of data. In the case of colonography, CAD has not been designed to cope with the presence of stool, although labeling the stool with high contrast agents replaces the use of laxatives and reduces the patient discomfort. This procedure introduces additional challenges for the diagnosis, such as poorly tagged stool, stool sticking to colonic walls, and heterogeneous stool (tagged stool mixed with air or untagged stool). Our study proposes a robust algorithm for heterogeneous stool removal to be employed as a preprocessing module for CAD systems in colonic cancer detection. Colonoscopy data are automatically cleansed of residual stool to enhance the polyp appearance for improved diagnosis. The algorithm uses expectationmaximization, quadratic regression, level sets and minimum variance. Results show stool removal accuracy on polyps which are partially or fully covered by stool. The results are robust on stool lining and large pools of heterogeneous and weakly-tagged stool. The automatic detection of colon polyps using our CAD system on cathartic-free data improves considerably with the addition of the automatic stool removal module from 74% to 86% true positive (TP) rate at 6.4 false positives (FP)/case.
AB - Computer-aided diagnosis (CAD) systems must show sufficient versatility to produce robust analysis on a large variety of data. In the case of colonography, CAD has not been designed to cope with the presence of stool, although labeling the stool with high contrast agents replaces the use of laxatives and reduces the patient discomfort. This procedure introduces additional challenges for the diagnosis, such as poorly tagged stool, stool sticking to colonic walls, and heterogeneous stool (tagged stool mixed with air or untagged stool). Our study proposes a robust algorithm for heterogeneous stool removal to be employed as a preprocessing module for CAD systems in colonic cancer detection. Colonoscopy data are automatically cleansed of residual stool to enhance the polyp appearance for improved diagnosis. The algorithm uses expectationmaximization, quadratic regression, level sets and minimum variance. Results show stool removal accuracy on polyps which are partially or fully covered by stool. The results are robust on stool lining and large pools of heterogeneous and weakly-tagged stool. The automatic detection of colon polyps using our CAD system on cathartic-free data improves considerably with the addition of the automatic stool removal module from 74% to 86% true positive (TP) rate at 6.4 false positives (FP)/case.
UR - http://www.scopus.com/inward/record.url?scp=61849104156&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=61849104156&partnerID=8YFLogxK
M3 - Conference contribution
C2 - 19163336
AN - SCOPUS:61849104156
SN - 9781424418152
SP - 2996
EP - 2999
BT - Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology"
ER -