C-peptide does not parallel increases of serum levels of substances immunologically cross-reactive with insulin in non-Hodgkin's lymphoma patients

K. Pavelic, S. Vuk Pavlovic

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

In 28 of 45 patients suffering from non-Hodgkin's lymphoma, the blood levels of substances detectable by the insulin-specific radioimmunoassay were supranormal, while the C-peptide levels were almost normal or even low. Such a ratio of these substances was also found in a diabetic non-Hodgkin's lymphoma patient. Two sera with the highest concentrations of these substances were investigated by gel filtration. In one case, the insulin cross-reactive material was eluted at the position of the insulin marker; in the other serum, its molecular mass was approximately 120,000.

Original languageEnglish (US)
Pages (from-to)925-928
Number of pages4
JournalBlood
Volume61
Issue number5
DOIs
StatePublished - 1983

ASJC Scopus subject areas

  • Biochemistry
  • Immunology
  • Hematology
  • Cell Biology

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