Burning mouth syndrome in Parkinson's disease: Dopamine as cure or cause?

Elizabeth A. Coon, Ruple S. Laughlin

Research output: Contribution to journalArticle

18 Scopus citations


Burning mouth syndrome has been reported as being more common in Parkinson's disease patients than the general population. While the pathophysiology is unclear, decreased dopamine levels and dopamine dysregulation are hypothesized to play a role. We report a patient with Parkinson's disease who developed burning mouth syndrome with carbidopa/levodopa. Our patient had resolution of burning mouth symptoms when carbidopa/ levodopa was replaced with a dopamine agonist. Based on our patient's clinical course, in conjunction with earlier studies assessing the relationship between burning mouth syndrome and Parkinson's disease, we discuss a potential role for dopamine in burning mouth syndrome in Parkinson's disease.

Original languageEnglish (US)
Pages (from-to)255-257
Number of pages3
JournalJournal of Headache and Pain
Issue number3
StatePublished - Apr 1 2012



  • Burning mouth syndrome
  • Carbidopa/levodopa
  • Dopamine
  • Pain
  • Parkinson's disease

ASJC Scopus subject areas

  • Clinical Neurology
  • Anesthesiology and Pain Medicine

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