Building a staircase to precision medicine for biliary tract cancer

Nataliya Razumilava; Gregory J. Gores

doi:10.1038/ng.3386

Building a staircase to precision medicine for biliary tract cancer

Nataliya Razumilava, Gregory J. Gores

Gastroenterology and Hepatology

Research output: Contribution to journal › Review article › peer-review

11 Scopus citations

Abstract

A new study has conducted a comprehensive exome and transcriptome analysis of a large number of intrahepatic, perihilar and distal cholangiocarcinomas and gallbladder cancers in Japanese patients. This study identifies many new alterations, confirms genetic differences in these distinct subtypes of biliary tract cancer and demonstrates that approximately 40% of described genetic aberrations are potentially targetable.

Original language	English (US)
Pages (from-to)	967-968
Number of pages	2
Journal	Nature Genetics
Volume	47
Issue number	9
DOIs	https://doi.org/10.1038/ng.3386
State	Published - Aug 27 2015

ASJC Scopus subject areas

Genetics

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10.1038/ng.3386

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abstract = "A new study has conducted a comprehensive exome and transcriptome analysis of a large number of intrahepatic, perihilar and distal cholangiocarcinomas and gallbladder cancers in Japanese patients. This study identifies many new alterations, confirms genetic differences in these distinct subtypes of biliary tract cancer and demonstrates that approximately 40% of described genetic aberrations are potentially targetable.",

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AB - A new study has conducted a comprehensive exome and transcriptome analysis of a large number of intrahepatic, perihilar and distal cholangiocarcinomas and gallbladder cancers in Japanese patients. This study identifies many new alterations, confirms genetic differences in these distinct subtypes of biliary tract cancer and demonstrates that approximately 40% of described genetic aberrations are potentially targetable.

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Building a staircase to precision medicine for biliary tract cancer

Abstract

ASJC Scopus subject areas

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