Building a robust, scalable and standards-driven infrastructure for secondary use of EHR data: The SHARPn project

Susan Rea, Jyotishman Pathak, Guergana Savova, Thomas A. Oniki, Les Westberg, Calvin E. Beebe, Cui Tao, Craig G. Parker, Peter J. Haug, Stanley M. Huff, Christopher G. Chute

Research output: Contribution to journalArticle

117 Scopus citations

Abstract

The Strategic Health IT Advanced Research Projects (SHARP) Program, established by the Office of the National Coordinator for Health Information Technology in 2010 supports research findings that remove barriers for increased adoption of health IT. The improvements envisioned by the SHARP Area 4 Consortium (SHARPn) will enable the use of the electronic health record (EHR) for secondary purposes, such as care process and outcomes improvement, biomedical research and epidemiologic monitoring of the nation's health. One of the primary informatics problem areas in this endeavor is the standardization of disparate health data from the nation's many health care organizations and providers. The SHARPn team is developing open source services and components to support the ubiquitous exchange, sharing and reuse or 'liquidity' of operational clinical data stored in electronic health records. One year into the design and development of the SHARPn framework, we demonstrated end to end data flow and a prototype SHARPn platform, using thousands of patient electronic records sourced from two large healthcare organizations: Mayo Clinic and Intermountain Healthcare. The platform was deployed to (1) receive source EHR data in several formats, (2) generate structured data from EHR narrative text, and (3) normalize the EHR data using common detailed clinical models and Consolidated Health Informatics standard terminologies, which were (4) accessed by a phenotyping service using normalized data specifications. The architecture of this prototype SHARPn platform is presented. The EHR data throughput demonstration showed success in normalizing native EHR data, both structured and narrative, from two independent organizations and EHR systems. Based on the demonstration, observed challenges for standardization of EHR data for interoperable secondary use are discussed.

Original languageEnglish (US)
Pages (from-to)763-771
Number of pages9
JournalJournal of Biomedical Informatics
Volume45
Issue number4
DOIs
StatePublished - Aug 2012

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Keywords

  • Electronic health records
  • Health information exchange
  • High-throughput phenotyping
  • Meaningful use
  • Natural language processing

ASJC Scopus subject areas

  • Computer Science Applications
  • Health Informatics

Cite this

Rea, S., Pathak, J., Savova, G., Oniki, T. A., Westberg, L., Beebe, C. E., Tao, C., Parker, C. G., Haug, P. J., Huff, S. M., & Chute, C. G. (2012). Building a robust, scalable and standards-driven infrastructure for secondary use of EHR data: The SHARPn project. Journal of Biomedical Informatics, 45(4), 763-771. https://doi.org/10.1016/j.jbi.2012.01.009