Bronchoscopic Phototherapy With Hematoporphyrin Derivative for Treatment of Localized Bronchogenic Carcinoma: A 5-Year Experience

ERIC S. EDELL, DENIS A. CORTESE

Research output: Contribution to journalArticlepeer-review

107 Scopus citations

Abstract

Between December 1980 and April 1986 at our institution, 38 patients with cancer that involved the tracheobronchial tree (a total of 40 carcinomas) completed at least one course of hematoporphyrin derivative phototherapy. A complete response occurred in 13 patients (with 14 carcinomas). Eleven of these carcinomas did not recur during follow-up periods that ranged from 3 to 53 months. Three carcinomas recurred at 9, 12, and 35 months, respectively. For 26 carcinomas, the response was less than complete, and alternative therapy was necessary. The carcinomas in patients with a complete response were radiographically occult, were less than 3 cm2 in surface area, and appeared superficial at bronchoscopy. Our experience supports the use of hematoporphyrin derivative phototherapy as an alternative to surgical resection in carefully selected patients.

Original languageEnglish (US)
Pages (from-to)8-14
Number of pages7
JournalMayo Clinic proceedings
Volume62
Issue number1
DOIs
StatePublished - 1987

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Bronchoscopic Phototherapy With Hematoporphyrin Derivative for Treatment of Localized Bronchogenic Carcinoma: A 5-Year Experience'. Together they form a unique fingerprint.

Cite this