Bronchiolitis: Pathologic considerations

Thomas V. Colby

Research output: Contribution to journalReview article

161 Scopus citations

Abstract

Bronchiolitis represents a cellular and mesenchymal reaction involving bronchioles. The interplay between the cellular infiltrate and the mesenchymal reaction affects the lumen size, lamina propria, muscular layer, and bronchiolar adventitia. The result is a variety of clinical, radiologic, and functional patterns of bronchiolar disease. The anatomy of the small airways is discussed, and a pathologic classification applicable to the surgical pathology of bronchiolitis is presented. The classification is practical and includes asthma, chronic obstructive pulmonary disease, cellular bronchiolitis, respiratory bronchiolitis, respiratory bronchiolitis- associated interstitial lung disease, bronchiolitis obliterans (including bronchiolitis obliterans with intraluminal polyps and constrictive bronchiolitis), dust-related small airway fibrosis, and (postinflammatory) bronchiolar scarring and peribronchiolar fibrosis.

Original languageEnglish (US)
Pages (from-to)101-109
Number of pages9
JournalAmerican journal of clinical pathology
Volume109
Issue number1
DOIs
StatePublished - Jan 1998

Keywords

  • Asthma
  • Bronchiolitis
  • Bronchiolitis obliterans
  • Constrictive bronchiolitis
  • Follicular bronchiolitis
  • Obliterative bronchiolitis
  • Respiratory bronchiolitis
  • Small airway diseases

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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