Bronchiectasis and Nontuberculous Mycobacterial Disease

David E. Griffith, Timothy R. Aksamit

Research output: Contribution to journalReview article

36 Scopus citations

Abstract

Over the last 30 years it has become increasingly clear that nontuberculous mycobacterial (NTM) lung infections and bronchiectasis are closely related disorders. Although incontrovertible proof is lacking, there is a growing consensus of opinion that NTM lung disease characterized by nodules and bronchiectasis (nodular/bronchiectatic NTM lung disease) may be a consequence of preexisting bronchiectasis that predisposes to NTM infection and disease. To use published diagnostic guidelines effectively, physicians must become familiar with the disease-causing potential of individual NTM species. Essentially all NTM patients have bronchiectasis, so optimal overall patient management requires successful therapeutic strategies for both NTM infection and bronchiectasis.

Original languageEnglish (US)
Pages (from-to)283-295
Number of pages13
JournalClinics in Chest Medicine
Volume33
Issue number2
DOIs
StatePublished - Jun 1 2012

Keywords

  • Bronchiectasis
  • Mycobacterium abscessus
  • Mycobacterium avium complex
  • Nontuberculous mycobacteria

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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