Abstract
Spatially selective excitation sequence CARVE (completely arbitrary regional volume excitation) excites signal from an arbitrarily shaped profile (I. Sersa, S. Macura: Magn. Reson. Med. 37, 920-931, 1997) by an interleaved sequence of precalculated small tip angle radio-frequency pulses and gradient pulses. Here we propose a spatially selective observation method based on the CARVE principles which is insensitive to the relaxation and the off-resonance effects. The method, CARVE-D (CARVE detection), excites spins uniformly across the sample and across the spectrum but achieves spatial selectivity by weighted coaddition of the signals after the data acquisition. CARVE-D is suitable for spatially selective high-resolution nuclear magnetic resonance spectroscopy in chemically and geometrically complex systems. The method is analyzed theoretically and demonstrated experimentally on model systems.
Original language | English (US) |
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Pages (from-to) | 277-290 |
Number of pages | 14 |
Journal | Applied Magnetic Resonance |
Volume | 22 |
Issue number | 2 |
DOIs | |
State | Published - 2002 |
ASJC Scopus subject areas
- Atomic and Molecular Physics, and Optics