Bridging vaccine ontology and NCIt vaccine domain for cancer vaccine data integration and analysis

Yongqun He, Guoqian D Jiang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The Vaccine Ontology (VO) is a community-based ontology in the domain of vaccines and vaccination. VO is aligned with the Basic Formal Ontology (BFO) and developed by following OBO Foundry principles. National Cancer Institute (NCI) Thesaurus (NCIt) serves as a reference ontology to facilitate interoperability and data sharing for cancer translational and basic research. To facilitate better cancer vaccine research, we compared the VO and NCIt vaccine domain (NCIt-vaccine) and examined the possibility of bridging and integrating these two ontologies. Our results showed that only a small portion of vaccine terms overlap between the two ontologies, and VO and NCIt-vaccine are complementary in different aspects. It is possible to integrate, map, and merge them. This study can be used as a use case for achieving the broader goal of merging and integrating NCIt and OBO library ontologies.

Original languageEnglish (US)
Title of host publicationCEUR Workshop Proceedings
PublisherCEUR-WS
Volume1515
StatePublished - 2015
EventInternational Conference on Biomedical Ontology, ICBO 2015 - Lisbon, Portugal
Duration: Jul 27 2015Jul 30 2015

Other

OtherInternational Conference on Biomedical Ontology, ICBO 2015
CountryPortugal
CityLisbon
Period7/27/157/30/15

ASJC Scopus subject areas

  • Computer Science(all)

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