Brentuximab vedotin

Research output: Contribution to journalReview article

53 Scopus citations

Abstract

Brentuximab vedotin is an anti-CD30 antibody-drug conjugate with proven efficacy in patients with CD30+ malignancies, including classical Hodgkin lymphoma and anaplastic large cell lymphoma. Promising activity has also been seen in other lymphomas that express CD30. Because of its acceptable toxicity profile and significant clinical efficacy, single-agent brentuximab vedotin is an approved treatment for relapsed patients with these diseases. Brentuximab vedotin has safely been combined with chemotherapy and is now being compared with standard treatments in randomized trials.

Original languageEnglish (US)
Pages (from-to)3197-3200
Number of pages4
JournalBlood
Volume124
Issue number22
DOIs
StatePublished - Nov 20 2014

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ASJC Scopus subject areas

  • Biochemistry
  • Immunology
  • Hematology
  • Cell Biology

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