Breath-hold MR measurements of blood flow velocity in internal mammary arteries and coronary artery bypass grafts

Hajime Sakuma, Sebastian Globits, Margaret O'Sullivan, Ann Shimakawa, Matthew A Bernstein, Thomas K F Foo, Thomas M. Amidon, Kan Takeda, Tsuyoshi Nakagawa, Charles B. Higgins

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Breath-hold velocity-encoded cine MR (VENC-MR) imaging is a feasible method for measuring phasic blood flow velocity in small vessels that move during respiration. The purposes of the current study are to compare breathhold VENC-MR measurements of flow velocities in the internal mammary arteries (IMA) with nonbreath-hold measurements and to characterize the systolic and diastolic flow velocity curves in a cardiac cycle in native IMA and IMA grafts. Flow velocity in 30 native IMA and 8 IMA grafts were evaluated with a breath-hold VENC-MR sequence with K-space segmentation and view-sharing reconstruction(TR/TE = 16/9 msec, VENC = 100 cm/s). In 10 native IMA, nonbreath-hold VENC-MR images were acquired as well for comparison. Breath-hold VENC-MR imaging showed significantly higher systolic and diastolic peak velocities in native IMA (43.1 cm/second ± 15.0 and 10.0 cm/second ± 4.8), in comparison to those of nonbreath-hold VENC-MR imaging (27.6 cm/second ± 10.2 and 7.3 cm/ second ± 3.9, P < .05). The diastolic/systolic peak velocity ratio in the IMA grafts (.88 ± .41) was significantly higher than that in native IMA (.24 ± .08, P < .01). Interobserver variability in the flow velocity measurement was less than 4%. Breath-hold VENC-MR imaging demonstrated higher peak flow velocity in the IMA than nonbreath-hold VENC-MR imaging. This technique is a rapid and effective method for the noninvasive assessment of blood flow velocity in IMA grafts.

Original languageEnglish (US)
Pages (from-to)219-222
Number of pages4
JournalJournal of Magnetic Resonance Imaging
Volume6
Issue number1
StatePublished - Jan 1996
Externally publishedYes

Fingerprint

Mammary Arteries
Blood Flow Velocity
Coronary Artery Bypass
Transplants
Observer Variation
Respiration

Keywords

  • Coronary artery bypass graft
  • Coronary flow
  • Internal mammary artery
  • Magnetic resonance imaging
  • Rapid MR imaging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Sakuma, H., Globits, S., O'Sullivan, M., Shimakawa, A., Bernstein, M. A., Foo, T. K. F., ... Higgins, C. B. (1996). Breath-hold MR measurements of blood flow velocity in internal mammary arteries and coronary artery bypass grafts. Journal of Magnetic Resonance Imaging, 6(1), 219-222.

Breath-hold MR measurements of blood flow velocity in internal mammary arteries and coronary artery bypass grafts. / Sakuma, Hajime; Globits, Sebastian; O'Sullivan, Margaret; Shimakawa, Ann; Bernstein, Matthew A; Foo, Thomas K F; Amidon, Thomas M.; Takeda, Kan; Nakagawa, Tsuyoshi; Higgins, Charles B.

In: Journal of Magnetic Resonance Imaging, Vol. 6, No. 1, 01.1996, p. 219-222.

Research output: Contribution to journalArticle

Sakuma, H, Globits, S, O'Sullivan, M, Shimakawa, A, Bernstein, MA, Foo, TKF, Amidon, TM, Takeda, K, Nakagawa, T & Higgins, CB 1996, 'Breath-hold MR measurements of blood flow velocity in internal mammary arteries and coronary artery bypass grafts', Journal of Magnetic Resonance Imaging, vol. 6, no. 1, pp. 219-222.
Sakuma, Hajime ; Globits, Sebastian ; O'Sullivan, Margaret ; Shimakawa, Ann ; Bernstein, Matthew A ; Foo, Thomas K F ; Amidon, Thomas M. ; Takeda, Kan ; Nakagawa, Tsuyoshi ; Higgins, Charles B. / Breath-hold MR measurements of blood flow velocity in internal mammary arteries and coronary artery bypass grafts. In: Journal of Magnetic Resonance Imaging. 1996 ; Vol. 6, No. 1. pp. 219-222.
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