Breath-held MR Cholangiopancreatography (MRCP) using a 3D Dixon fat-water separated balanced steady state free precession sequence

James F. Glockner, Manojkumar Saranathan, Ersin Bayram, Christine U. Lee

Research output: Contribution to journalArticle

20 Scopus citations

Abstract

A novel 3D breath-held Dixon fat-water separated balanced steady state free precession (b-SSFP) sequence for MR cholangiopancreatography (MRCP) is described and its potential clinical utility assessed in a series of patients. The main motivation is to develop a robust breath-held alternative to the respiratory gated 3D Fast Spin Echo (FSE) sequence, the current clinical sequence of choice for MRCP. Respiratory gated acquisitions are susceptible to motion artifacts and blurring in patients with significant diaphragmatic drift, erratic respiratory rhythms or sleep apnea. A two point Dixon fat-water separation scheme was developed which eliminates signal loss arising from B0 inhomogeneity effects and minimizes artifacts from perturbation of the b-SSFP steady state. Preliminary results from qualitative analysis of 49 patients demonstrate robust performance of the 3D Dixon b-SSFP sequence with diagnostic image quality acquired in a 20-24s breath-hold.

Original languageEnglish (US)
Pages (from-to)1263-1270
Number of pages8
JournalMagnetic Resonance Imaging
Volume31
Issue number8
DOIs
StatePublished - Oct 1 2013

Keywords

  • Biliary
  • MRCP
  • Steady state free precession

ASJC Scopus subject areas

  • Biophysics
  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

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