Brain lesions in cerebral venous sinus thrombosis

Alexander Y. Zubkov, Robert D. McBane, Robert D Jr. Brown, Alejandro Rabinstein

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Background and Purpose - Analyze the relationship between the location and extent of sinus thrombosis and presence and severity of brain lesions. Methods - Retrospective chart and neuroimaging review of patients with documented CVST. A CVST score was devised to quantify the extent of cerebral venous sinus thrombosis. Results - Nineteen of 56 (34%) patients had brain lesions. The extent of sinus thrombus was associated with increased risk of brain lesions (CVST score 1.9 among patients without brain lesions versus 3.1 in those with lesions; P=0.006). Age, sex, and acquired or hereditary thrombophilias were not associated with the risk of parenchymal lesions. Functional outcomes were favorable even in patients with extensive CVST and parenchymal lesions at presentation. Conclusions-The extent of the sinus involvement correlates with the risk of brain lesions in patients with CVST, but additional factors might also contribute to their occurrence.

Original languageEnglish (US)
Pages (from-to)1509-1511
Number of pages3
JournalStroke
Volume40
Issue number4
DOIs
StatePublished - Apr 1 2009

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Intracranial Sinus Thrombosis
Venous Thrombosis
Brain
Neuroimaging
Thrombosis

Keywords

  • Cerebral sinus
  • Hemorrhage
  • Neuroimaging
  • Stroke
  • Thrombosis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Clinical Neurology
  • Advanced and Specialized Nursing
  • Medicine(all)

Cite this

Brain lesions in cerebral venous sinus thrombosis. / Zubkov, Alexander Y.; McBane, Robert D.; Brown, Robert D Jr.; Rabinstein, Alejandro.

In: Stroke, Vol. 40, No. 4, 01.04.2009, p. 1509-1511.

Research output: Contribution to journalArticle

Zubkov, Alexander Y. ; McBane, Robert D. ; Brown, Robert D Jr. ; Rabinstein, Alejandro. / Brain lesions in cerebral venous sinus thrombosis. In: Stroke. 2009 ; Vol. 40, No. 4. pp. 1509-1511.
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