BRAF V600E Expression in Primary Melanoma and Its Association With Death: A Population-Based, Retrospective, Cross-Sectional Study

Jamison A. Harvey, Julia S. Lehman, Christine M. Lohse, Alanna M. Chamberlain, Svetomir N. Markovic, Celine M. Vachon, Jerry D. Brewer

Research output: Contribution to journalArticlepeer-review

Abstract

Approximately 50% of melanomas contain BRAF mutations; the effects on survival are unclear. We aimed to determine whether mutant BRAF expression in melanoma differs according to age, sex, and melanoma-specific survival. A total of 638 patients who resided in Olmsted County, Minnesota, with a first lifetime diagnosis of melanoma between 1970 and 2009 were identified from the Rochester Epidemiology Project (REP). Available tissue was analyzed for a BRAF V600E mutation with immunohistochemistry.

Original languageEnglish (US)
JournalCutis
Volume109
Issue number5
DOIs
StatePublished - May 2022

ASJC Scopus subject areas

  • Medicine(all)

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