Brachial approach to NOGA-guided procedures

Electromechanical mapping and transendocardial stem-cell injections

Marko Banovic, Miodrag C. Ostojic, Jozef Bartunek, Milan Nedeljkovic, Branko Beleslin, Andre Terzic

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Several methods are available for delivering stem cells to the heart. Recent studies have highlighted the advantages of injecting the cells directly into the myocardium in order to increase myocardial retention of cells. A particular focus has been on percutaneous transendocardial injection, facilitated by electromechanical mapping. The NOGA® XP Cardiac Navigation System has a multicomponent catheter that is designed to guide and deliver transendocardial injections via a transfemoral approach, without a guidewire. However, this method may not be feasible in some patients who have peripheral vascular disease. Herein, we describe the case of a 68-year-old man whose tortuous, sharply angled iliac arteries precluded a femoral approach to transendocardial injection. To overcome the anatomic and mechanical challenges, we used a brachial approach. We believe that this is the 1st report of using the brachial route for transendocardial injection, and that it can be a viable alternative to the transfemoral approach in selected patients.

Original languageEnglish (US)
Pages (from-to)179-182
Number of pages4
JournalTexas Heart Institute Journal
Volume38
Issue number2
StatePublished - 2011

Fingerprint

Arm
Stem Cells
Injections
Peripheral Vascular Diseases
Iliac Artery
Thigh
Myocardium
Catheters

Keywords

  • Biological products/therapeutic use
  • Coronary vessels/pathology
  • Electrophysiologic techniques, cardiac/instrumentation/methods
  • Heart diseases/therapy
  • Imaging, three-dimensional
  • Injections
  • Myocardial infarction/pathology
  • Regenerative medicine/methods
  • Stem cell transplantation/methods
  • Treatment outcome

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Brachial approach to NOGA-guided procedures : Electromechanical mapping and transendocardial stem-cell injections. / Banovic, Marko; Ostojic, Miodrag C.; Bartunek, Jozef; Nedeljkovic, Milan; Beleslin, Branko; Terzic, Andre.

In: Texas Heart Institute Journal, Vol. 38, No. 2, 2011, p. 179-182.

Research output: Contribution to journalArticle

Banovic, M, Ostojic, MC, Bartunek, J, Nedeljkovic, M, Beleslin, B & Terzic, A 2011, 'Brachial approach to NOGA-guided procedures: Electromechanical mapping and transendocardial stem-cell injections', Texas Heart Institute Journal, vol. 38, no. 2, pp. 179-182.
Banovic, Marko ; Ostojic, Miodrag C. ; Bartunek, Jozef ; Nedeljkovic, Milan ; Beleslin, Branko ; Terzic, Andre. / Brachial approach to NOGA-guided procedures : Electromechanical mapping and transendocardial stem-cell injections. In: Texas Heart Institute Journal. 2011 ; Vol. 38, No. 2. pp. 179-182.
@article{f958b2ff50a5476891a0bc0961ef9a39,
title = "Brachial approach to NOGA-guided procedures: Electromechanical mapping and transendocardial stem-cell injections",
abstract = "Several methods are available for delivering stem cells to the heart. Recent studies have highlighted the advantages of injecting the cells directly into the myocardium in order to increase myocardial retention of cells. A particular focus has been on percutaneous transendocardial injection, facilitated by electromechanical mapping. The NOGA{\circledR} XP Cardiac Navigation System has a multicomponent catheter that is designed to guide and deliver transendocardial injections via a transfemoral approach, without a guidewire. However, this method may not be feasible in some patients who have peripheral vascular disease. Herein, we describe the case of a 68-year-old man whose tortuous, sharply angled iliac arteries precluded a femoral approach to transendocardial injection. To overcome the anatomic and mechanical challenges, we used a brachial approach. We believe that this is the 1st report of using the brachial route for transendocardial injection, and that it can be a viable alternative to the transfemoral approach in selected patients.",
keywords = "Biological products/therapeutic use, Coronary vessels/pathology, Electrophysiologic techniques, cardiac/instrumentation/methods, Heart diseases/therapy, Imaging, three-dimensional, Injections, Myocardial infarction/pathology, Regenerative medicine/methods, Stem cell transplantation/methods, Treatment outcome",
author = "Marko Banovic and Ostojic, {Miodrag C.} and Jozef Bartunek and Milan Nedeljkovic and Branko Beleslin and Andre Terzic",
year = "2011",
language = "English (US)",
volume = "38",
pages = "179--182",
journal = "Texas Heart Institute Journal",
issn = "0730-2347",
publisher = "Texas Heart Institute",
number = "2",

}

TY - JOUR

T1 - Brachial approach to NOGA-guided procedures

T2 - Electromechanical mapping and transendocardial stem-cell injections

AU - Banovic, Marko

AU - Ostojic, Miodrag C.

AU - Bartunek, Jozef

AU - Nedeljkovic, Milan

AU - Beleslin, Branko

AU - Terzic, Andre

PY - 2011

Y1 - 2011

N2 - Several methods are available for delivering stem cells to the heart. Recent studies have highlighted the advantages of injecting the cells directly into the myocardium in order to increase myocardial retention of cells. A particular focus has been on percutaneous transendocardial injection, facilitated by electromechanical mapping. The NOGA® XP Cardiac Navigation System has a multicomponent catheter that is designed to guide and deliver transendocardial injections via a transfemoral approach, without a guidewire. However, this method may not be feasible in some patients who have peripheral vascular disease. Herein, we describe the case of a 68-year-old man whose tortuous, sharply angled iliac arteries precluded a femoral approach to transendocardial injection. To overcome the anatomic and mechanical challenges, we used a brachial approach. We believe that this is the 1st report of using the brachial route for transendocardial injection, and that it can be a viable alternative to the transfemoral approach in selected patients.

AB - Several methods are available for delivering stem cells to the heart. Recent studies have highlighted the advantages of injecting the cells directly into the myocardium in order to increase myocardial retention of cells. A particular focus has been on percutaneous transendocardial injection, facilitated by electromechanical mapping. The NOGA® XP Cardiac Navigation System has a multicomponent catheter that is designed to guide and deliver transendocardial injections via a transfemoral approach, without a guidewire. However, this method may not be feasible in some patients who have peripheral vascular disease. Herein, we describe the case of a 68-year-old man whose tortuous, sharply angled iliac arteries precluded a femoral approach to transendocardial injection. To overcome the anatomic and mechanical challenges, we used a brachial approach. We believe that this is the 1st report of using the brachial route for transendocardial injection, and that it can be a viable alternative to the transfemoral approach in selected patients.

KW - Biological products/therapeutic use

KW - Coronary vessels/pathology

KW - Electrophysiologic techniques, cardiac/instrumentation/methods

KW - Heart diseases/therapy

KW - Imaging, three-dimensional

KW - Injections

KW - Myocardial infarction/pathology

KW - Regenerative medicine/methods

KW - Stem cell transplantation/methods

KW - Treatment outcome

UR - http://www.scopus.com/inward/record.url?scp=79955094247&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79955094247&partnerID=8YFLogxK

M3 - Article

VL - 38

SP - 179

EP - 182

JO - Texas Heart Institute Journal

JF - Texas Heart Institute Journal

SN - 0730-2347

IS - 2

ER -